Results 111 to 120 of about 3,740 (175)

TAF1 wt Allele [PDF]

, 2020
openaire   +1 more source

Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC

Discover Oncology
Background T cell exhaustion (TEX) signifies a condition of T cell disorder which implicate the therapeutic benefits and prognostic significance in patients with cancer.
Wei Zhang, Mei Qu, Chun Yin, Zhiliang Jin, Ya Hu   +4 more
doaj   +1 more source

Neuron-Specific Function of N-TAF1, the disease causative gene of Hereditary Dystonia(DYT3)

, 2012
科学研究費補助金研究成果報告書研究種目: 若手研究(B)研究期間: 2010～2011課題番号: 22790332研究代表者: 牧野 悟士（滋賀医科大学・分子神経科学研究センター・特任助教）遺伝性ジストニアDYT3の原因遺伝子TAF1の神経細胞特異的なアイソフォームに関して、神経細胞における役割を明らかにすることを目的として、神経系および非神経系の哺乳類培養細胞株における強制発現を行い、細胞内局在のパターンを調べた。その結果、両者の間で局在パターンに差異のあることがわかった。また、N ...
牧野,　悟士, MAKINO, Satoshi
core  

Functional characterization of the COOH-terminal kinase activity of the TBP-associated factor TAF1

, 2006
Activation of eukaryotic transcription involves an orchestrated interplay between transcription factors and the general RNA polymerase II (Pol II) transcription machinery (GTM), which consists of Pol II and general transcription factors (GTFs).
Maile, Tobias
core  

Funktionelle Charakterisierung der COOH-terminalen Kinaseaktivität des TBP-assoziierten Faktors TAF1

, 2006
Activation of eukaryotic transcription involves an orchestrated interplay between transcription factors and the general RNA polymerase II (Pol II) transcription machinery (GTM), which consists of Pol II and general transcription factors (GTFs).
Maile, Tobias
core  

TAF1 aggravates ferroptosis by promoting the ubiquitin-mediated degradation of nuclear GPX4. [PDF]

J Zhejiang Univ Sci B
Ye K, Gan M, Sun L, Chen C, Lai X, He Y, Zhu M, Jiang W, Zhang H.   +8 more
europepmc   +1 more source

Mitochondrial toxins cause widespread downregulation of pathways in X-linked dystonia-parkinsonism patient-derived neurons. [PDF]

Stem Cell Reports
Grütz K, Künstner A, Krause C, Santinelli L, Franzenburg S, Ghelfi J, Grünewald A, Rosales RL, Brüggemann N, Busch H, Klein C, Seibler P.   +11 more
europepmc   +1 more source

Androgen receptor modulation by non-androgenic factors and the basal transcription factor TAF1

, 2010
There is considerable evidence to suggest that progression of prostate cancers to castration-resistant is due to inappropriate activation of the androgen receptor (AR) and hence, the AR is a good target for the treatment of this disease. In this study we
Tavassoli, Peyman
core  

TAF1 acetyltransferase promotes colorectal carcinoma metastasis by catalyzing β-hydroxybutyrylation of KCTD9. [PDF]

Oncogene
Su J, Zhao M, Feng W, Lin Y, Lu X, Xia Z, Cheng T, Liu Q, Cheng L, Pu C, Zhang A, Tang J, Yu B.   +12 more
europepmc   +1 more source

PROTAC-Mediated Degradation of TAF1 Induces Apoptosis in AML Cells and Inhibits Tumor Growth In Vivo. [PDF]

Mol Cancer Ther
Chen L, Shultz ZP, Sansone M, Fang B, Liu X, Teng M, Schonbrunn E, Lopchuk JM, Chen J.   +8 more
europepmc   +1 more source