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Taf1: A class II transposon of Aspergillus fumigatus
Fungal Genetics and Biology, 2005Aspergillus fumigatus is an important medical pathogen that lacks a known sexual cycle. Transposons may provide an important mechanism for the generation of genetic diversity in this organism. Here, we describe Taf1, the first class II transposon to be identified in A. fumigatus. Taf1, a member of the mariner superfamily and pogo family of transposons,
Franz, Monroy, Donald C, Sheppard
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Regulated expression of TAF1 in 1-cell mouse embryos
Zygote, 2006SummaryTATA binding protein (TBP) associated factor 1 (TAF1) is a member of the general transcription machinery. Interference in the function of TAF1 causes a broad transcriptional defect in early development. To explore possible roles of TAF1 in embryonic transcriptional silence and zygotic genome activation, we examined the expression of TAF1 in 1 ...
Kai, Wang, Feng, Sun, Hui Z, Sheng
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Evidence of TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism
Cellular and Molecular Life Sciences, 2016The molecular dysfunction in X-linked dystonia-parkinsonism is not completely understood. Thus far, only noncoding alterations have been found in genetic analyses, located in or nearby the TATA-box binding protein-associated factor 1 (TAF1) gene. Given that this gene is ubiquitously expressed and is a critical component of the cellular transcription ...
Aloysius Domingo +15 more
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THE ROLE OF TAF1 AND CTCF IN HIV LATENCY
Despite the effectiveness of combination antiretroviral therapy (cART) in suppressing HIV-1 replication, it cannot eliminate the virus due to the persistence of a latent reservoir in long-lived CD4⁺ T cells. These transcriptionally silent proviruses evade immune clearance and represent a major barrier to HIV cure strategies.openaire +1 more source
TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1
Biochemical and Biophysical Research Communications, 2022Boxiang Zhang, Xiaohai Cui
exaly
Molecular diagnosis due to a hemizygous TAF1 Variant
This case report describes an 8-year-old male with a complex clinical presentation characterized by global developmental delay and refractory epilepsy. His medical history is significant for a term birth complicated by umbilical cord avulsion during a water delivery.openaire +1 more source
TAF1 expression in X-Linked Dystonia-Parkinsonism (534)
Neurology, 2020Jamal Al Ali +9 more
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