Results 151 to 160 of about 4,594 (188)

Retrotransposon: an insight into neurological disorders from perspectives of neurodevelopment and aging. [PDF]

Transl Neurodegener
Zhang W, Huang C, Yao H, Yang S, Jiapaer Z, Song J, Wang X.   +6 more
europepmc   +1 more source

TAF1, the Largest Subunit of Tfiid, Is Dispensable for Adult Hematopoiesis

Blood, 2023
Temporal and spatial control of gene expression is central to normal hematopoietic stem cell (HSC) biology. Many sequence-specific transcription factors have been identified as key regulators of HSC fate decision, while the function of general ...
Fan Liu, Jing-Yin Yue, F. Tamiro, Jun Sun, P. Cingaram, K. Hossack, Concepcion Martinza Caja, F. Beckedorff, R. Shiekhattar, S. Nimer   +9 more
semanticscholar   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Targeting TAF1 with BAY-299 induces antitumor immunity in triple-negative breast cancer

Biochemical and Biophysical Research Communications, 2023
Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype with poor prognoses and limited therapeutic options. The TATA-box binding protein associated factor 1 (TAF1) is an essential protein involved in the transcriptional regulation ...
Wenjun Chen, Xueying Liu, Kejing Zhang
exaly   +2 more sources

TAF1 promotes NSCLC cell epithelial-mesenchymal transition by transcriptionally activating TGFβ1

Biochemical and Biophysical Research Communications, 2022
Despite tremendous advances in the diagnosis and treatment of NSCLC, the morbidity and mortality of NSCLC still rank high worldwide. Epithelial-mesenchymal transition (EMT) is vital to the invasion, metastasis, and recurrence of NSCLC. Unfortunately, the
Boxiang Zhang
exaly   +2 more sources

Taf1: A class II transposon of Aspergillus fumigatus

Fungal Genetics and Biology, 2005
Aspergillus fumigatus is an important medical pathogen that lacks a known sexual cycle. Transposons may provide an important mechanism for the generation of genetic diversity in this organism. Here, we describe Taf1, the first class II transposon to be identified in A. fumigatus. Taf1, a member of the mariner superfamily and pogo family of transposons,
Franz, Monroy, Donald C, Sheppard
openaire   +2 more sources

Identification and localization of a neuron-specific isoform of TAF1 in rat brain: implications for neuropathology of DYT3 dystonia.

Neuroscience, 2011
The neuron-specific isoform of the TAF1 gene (N-TAF1) is thought to be involved in the pathogenesis of DYT3 dystonia, which leads to progressive neurodegeneration in the striatum.
Ann Graybiel, S Nagahiro, I Tooyama
exaly   +2 more sources

Regulated expression of TAF1 in 1-cell mouse embryos

Zygote, 2006
SummaryTATA binding protein (TBP) associated factor 1 (TAF1) is a member of the general transcription machinery. Interference in the function of TAF1 causes a broad transcriptional defect in early development. To explore possible roles of TAF1 in embryonic transcriptional silence and zygotic genome activation, we examined the expression of TAF1 in 1 ...
Kai, Wang, Feng, Sun, Hui Z, Sheng
openaire   +2 more sources

TAF1 is needed for the proliferation and maturation of thyroid follicle cells via Notch signaling.

American Journal of Physiology. Endocrinology and Metabolism
Thyroid dysgenesis (TD) is the common pathogenic mechanism of congenital hypothyroidism (CH). In addition, known pathogenic genes are limited to those that are directly involved in thyroid development. To identify additional candidate pathogenetic genes,
Caoxu Zhang, Liu Yang, Hai-Yang Zhang, Feng-Yao Wu, Yue Zhang, Kai-Wen Zhang, Chen-Yang Wu, Rui Li, M. Dong, Shuang-Xia Zhao, Huai-Dong Song   +10 more
semanticscholar   +1 more source

Advancements in the Study of Clinical Features and Molecular Functions in Heterogeneous TAF1-associated Clinical Phenotypes

Clinical Neuroscience Research
Purpose of review: TATA-binding protein (TBP)-associated factor 1 (TAF1) encodes the largest component of the transcription factor IID (TFIID) complex, which binds to core promoters and serves as a scaffold for assembly of the RNA polymerase II ...
Hui Xiao, Jing Peng, Lei-Lei Mao
semanticscholar   +1 more source

Abidi Syndrome and Another Family With X-Linked Intellectual Disability Have TAF1 Variants and Reduced Phosphorylation of RNA Polymerase II Associated Protein 74.

American Journal of Medical Genetics. Part A
Genetic alterations in TATA box binding protein-associated factor 1 (TAF1) have been found in an X-linked intellectual disability (XLID) syndrome with variable somatic features (OMIM 300966) and X-linked dystonia-Parkinsonism syndrome (OMIM 314250 ...
Mei Han, F. Abidi, C. Skinner, Sujata Srikanth, Rui-Hua Wang, T. Niranjan, Charles E. Schwartz, R. Stevenson, Tao Wang   +8 more
semanticscholar   +1 more source