Results 161 to 170 of about 4,594 (188)

m6A‐Modulated RNF14 Favors Fatty Acid Oxidation to Drive Colorectal Cancer Progression via Regulation of TAF1/PINK1 Axis

The FASEB Journal
The contribution of fatty acid oxidation (FAO) to colorectal cancer (CRC) progression has been recognized. However, the detailed mechanisms underlying FAO remain obscure.
Lv Lv, Fa-You Lv, Bin-Feng Li, Guo-Qing Li, H. Yi   +4 more
semanticscholar   +1 more source

Evidence of TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism

Cellular and Molecular Life Sciences, 2016
The molecular dysfunction in X-linked dystonia-parkinsonism is not completely understood. Thus far, only noncoding alterations have been found in genetic analyses, located in or nearby the TATA-box binding protein-associated factor 1 (TAF1) gene. Given that this gene is ubiquitously expressed and is a critical component of the cellular transcription ...
Aloysius Domingo, David Amar, Karen Grütz, Lillian V. Lee, Raymond Rosales, Norbert Brüggemann, Roland Dominic Jamora, Eva Cutiongco-dela Paz, Arndt Rolfs, Dirk Dressler, Uwe Walter, Dimitri Krainc, Katja Lohmann, Ron Shamir, Christine Klein, Ana Westenberger   +15 more
openaire   +2 more sources

TAF1 and GCN5‐mediated histone acetylation of regulatory cascade AHL14/17‐A/NINV7 promotes sucrose catabolism and sugar accumulation for cold tolerance in Citrus

New Phytologist
Sugar metabolism plays a vital role in plant cold tolerance. Histone acetyltransferases (HATs) act as key epigenetic regulators of stress‐responsive genes, yet the function and mechanism underlying HAT‐mediated histone acetylation (HA) in regulation of ...
B. Dahro, Madiha Khan, Le-Le Chu, Jian Zhu, Xiangming Shang, Xi Zeng, Xiao-Yu Wu, Wen-Qian Hu, Xue-Lei Lai, Chun-Long Li, Ji-Hong Liu   +10 more
semanticscholar   +1 more source

THE ROLE OF TAF1 AND CTCF IN HIV LATENCY

Despite the effectiveness of combination antiretroviral therapy (cART) in suppressing HIV-1 replication, it cannot eliminate the virus due to the persistence of a latent reservoir in long-lived CD4⁺ T cells. These transcriptionally silent proviruses evade immune clearance and represent a major barrier to HIV cure strategies.
openaire   +1 more source

Molecular diagnosis due to a hemizygous TAF1 Variant

This case report describes an 8-year-old male with a complex clinical presentation characterized by global developmental delay and refractory epilepsy. His medical history is significant for a term birth complicated by umbilical cord avulsion during a water delivery.
openaire   +1 more source

MERGED SCAFFOLD TAF1 INHIBITORS

2022
LOPCHUK JUSTIN, SCHONBRUNN ERNST, SHULTZ ZACHARY, KARIM MD REZAUL, CHEN JIANDONG   +4 more
openaire   +1 more source

TAF1 expression in X-Linked Dystonia-Parkinsonism (534)

Neurology, 2020
Jamal Al Ali, Shivangi Shah, Christine A. Vaine, Naoto Ito, William Hendriks, Benjamin Currall, Michael Talkowski, Laurie Ozelius, Cristopher Bragg, Xandra Breakefield   +9 more
openaire   +1 more source

COMPOUNDS FOR TARGETED DEGRADATION OF TAF1

2023
LOPCHUK JUSTIN, SCHONBRUNN ERNST, CHEN JIANDONG, SHULTZ ZACHARY   +3 more
openaire   +2 more sources

TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-linked Dystonia-Parkinsonism

Movement Disorders, 2021
Xandra O. Breakefield, Jamal Al Ali, Laurie Ozelius   +2 more
exaly  

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity

Pathology and Oncology Research, 2016
Sug Hyung Lee, Nam Jin Yoo, Chang Hyeok An   +2 more
exaly