Results 91 to 100 of about 5,684 (155)

Delays in diagnosis and treatment of ATTR cardiac amyloidosis: A real‐world data analysis

ESC Heart Failure
Aims and Background Cardiac amyloidosis leads to functional cardiac impairment and heart failure. Transthyretin amyloid cardiomyopathy (ATTR‐CM) is the most common form.
Julia Vogel, Sophia Jura, Stephan Settelmeier, Florian Buehning, Tobias Lerchner, Alexander Carpinteiro, Tienush Rassaf, Lars Michel   +7 more
doaj   +1 more source

Real-World Outcomes Among Patients in the United States Receiving Tafamidis for Transthyretin Amyloid Cardiomyopathy

Cardiology and Therapy
Introduction Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, often fatal disease. Tafamidis demonstrated efficacy in ATTR-CM clinical trials; however, real-world disease outcomes are not thoroughly characterized.
Daniel P. Judge, Margarita Udall, Andrew M. Rosen, Neil Lamarre, Elizabeth Nagelhout, Hanh Dung Dao, Mathew S. Maurer   +6 more
doaj   +1 more source

Safety assessment of Tafamidis: a real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events

SAFETY ASSESSMENT OF TAFAMIDIS: A REAL-WORLD PHARMACOVIGILANCE STUDY OF FDA ADVERSE EVENT REPORTING SYSTEM (FAERS) EVENTS Safety assessment of Tafamidis: a real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events / Li ...
Li, Yidan, Sun, Shengzhu, Zhao, Leiyong, Wu, Hongyun, Peng, Wei   +4 more
core  

Effects of Tafamidis Meglumine on Transient Focal Neurological Episodes and Meningeal Contrast Enhancement in Hereditary Transthyretin‐Related Meningeal Amyloidosis: Report of Two Patients Carrying the c.265T>C (p.Y89H) Variant

Brain and Behavior
Background Y69H (p.Y89H) variant hereditary transthyretin (ATTRv) amyloidosis causes meningeal amyloidosis, with mutant TTR deposits localized to the leptomeninges and vitreous body.
Natsumi Saito, Yasuko Kuroha, Ayaka Ishiyama, Takahiro Wakasugi, Takayoshi Tokutake, Arika Hasegawa, Tetsuya Takahashi   +6 more
doaj   +1 more source

Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis

, 2018
Oculomeningovascular amyloidosis is a variant of transthyretin (TTR) amyloidotic polyneuropathy, which is associated with blindness and brain ischemia, microhemorrages, and siderosis due to prominent production of the abnormal TTR in the eye and in the ...
Volpe, Roberto, Vella, Alessandra, Alessandra Vella, Bianchi, Andrea, Rapezzi, Claudio, Claudio Rapezzi, Francesca Pastorelli, Roberto Volpe, Salvi, Fabrizio, Mascalchi, Mario, Fabrizio Salvi, Mario Mascalchi, Pastorelli, Francesca, Andrea Bianchi   +13 more
core   +1 more source

Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis

JACC: Advances
Background: Atrial fibrillation/flutter (AF) is common in transthyretin cardiac amyloidosis (ATTR-CA). The CHARGE-AF score has not been validated in ATTR-CA.
Nicholas Chan, MD, MS, Yevgeniy Brailovsky, DO, MSc, Sergio Teruya, MD, MS, Alfonsina Mirabal, MD, Ariel Y. Weinsaft, Jeffeny De Los Santos, MD, MHA, Samantha Guadalupe, MHA, Massiel Jimenez, MD, Stephen Helmke, RDCS, MPH, Margaret Cuomo, MSN, FNP-C, Dia Smiley, DO, Angelo Biviano, MD, Jose Dizon, MD, Elaine Wan, MD, Hirad Yarmohammadi, MD, Mathew S. Maurer, MD   +15 more
doaj   +1 more source

Management of Cardiac Amyloidosis: A Narrative Review

Journal of the Practice of Cardiovascular Sciences
Amyloidosis is a multi-system disorder in which cardiac involvement often manifests with heart failure and/or arrhythmias. Recognition of cardiac amyloidosis is important as it is a potentially treatable cause of cardiomyopathy.
Neha Chopra, Rishi Dhawan, Sandeep Seth
doaj   +1 more source

Baseline Predictors of Adverse Outcomes for Transthyretin Amyloidosis Cardiomyopathy Patients Treated and Untreated with Tafamidis: A Canadian Referral Center Experience

Background: Tafamidis is a costly therapy that improves outcomes for patients with transthyretin amyloidosis cardiomyopathy (ATTR-CM), although significant knowledge gaps exist for predicting longer-term response to treatment.
Jonathan G. Howlett, Jan Veenhuyzen, Victor Jimenez-Zepeda, Steven Dykstra, Karan Shahi, Robert J. H. Miller, Yuanchao Feng, Nowell M. Fine, James A. White   +8 more
core   +1 more source

Tafamidis in the Treatment of ATTR-related Cardiomyopathy

: Transthyretin amyloid cardiomyopathy (ATTR-CM) is caused by the myocardial extracellular deposition of amyloid fibrils formed from the dissociation of TTR tetramer into monomers.
Lalario, Andrea, Rossi, Maddalena, Porcari, Aldostefano, Emdin, Michele, Sinagra, Gianfranco, Aimo, Alberto, Limongelli, Giuseppe, Capovilla, Teresa Maria, Merlo, Marco   +8 more
core   +1 more source

Gender and Racial Distribution of Transthyretin Stabilizer Therapy in Patients With Transthyretin Cardiac Amyloidosis. [PDF]

JACC Adv
Foley SJ, Hegde S.
europepmc   +1 more source