Results 161 to 170 of about 3,514 (179)

Elucidating the effect of drug-induced mitochondrial dysfunction on insulin signaling and glucose handling in skeletal muscle cell line (C2C12) in vitro. [PDF]

PLoS One
Kuretu A, Mothibe M, Ngubane P, Sibiya N.   +3 more
europepmc   +1 more source

Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells. [PDF]

Sci Rep
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Teixeira da Rosa N, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML.   +12 more
europepmc   +1 more source

Correction: Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome. [PDF]

Dis Model Mech
Damschroder D, Zapata-Pérez R, Richardson K, Vaz FM, Houtkooper RH, Wessells R.   +5 more
europepmc   +1 more source

Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome. [PDF]

Diabetologia
Carlein C, Hoffmann MDA, Bickelmann C, Amaral AG, Lotfinia A, de Selliers LA, Audouze-Chaud J, Wrublewsky S, Lauterbach MA, von der Malsburg K, van der Laan M, Bozem M, Hoth M, Gilon P, Ravier MA, Morgan B, Ampofo E, Higuchi T, Bertero E, Dudek J, Maack C, Roma LP.   +21 more
europepmc   +1 more source

SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism. [PDF]

PLoS One
Liu LX, Zheng XH, Hai JH, Zhang CM, Ti Y, Chen TS, Bu PL.   +6 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Tafazzin splice variants and mutations in Barth syndrome

Molecular Genetics and Metabolism, 2014
Barth syndrome is caused by mutations in the TAZ (tafazzin) gene on human chromosome Xq28. The human tafazzin gene produces four major mRNA splice variants; two of which have been shown to be functional (TAZ lacking exon 5 and full-length) in complementation studies with yeast and Drosophila.
Susan M, Kirwin, Athena, Manolakos, Sarah Swain, Barnett, Iris L, Gonzalez   +3 more
openaire   +2 more sources

Cardiac mitochondrial structure and function in tafazzin-knockdown mice

Mitochondrion, 2018
Mutations in the tafazzin gene are the basis of Barth syndrome. The tafazzin protein is responsible for the synthesis of cardiolipin. Doxycycline-induced tafazzin-knockdown mice have been used as a model for Barth syndrome. In the current study, we examined subsarcolemmal and interfibrillar mitochondria from hearts of tafazzin-knockdown mice, focusing ...
Junhwan Kim, Kwangwon Lee, Hisashi Fujioka, Bernard Tandler, Charles L. Hoppel   +4 more
openaire   +2 more sources

Cardiolipin remodeling and the function of tafazzin

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2013
Cardiolipin, the specific phospholipid of mitochondria, is involved in the biogenesis, the dynamics, and the supramolecular organization of mitochondrial membranes. Cardiolipin acquires a characteristic composition of fatty acids by post-synthetic remodeling, a process that is crucial for cardiolipin homeostasis and function.
openaire   +2 more sources

A Reduction in Tafazzin Decreases Mitochondrial Function in C2C12 Myotubes

The FASEB Journal, 2022
Mitochondria, which are often regarded as the “powerhouse of the cell”, are labile organelles that regulate cellular metabolism, determine cell fate, and act as important signaling hubs. A phospholipid that is exclusively found within mitochondria that serves numerous roles is cardiolipin (CL).
Brandon J. Richards, Ashley N. Oliviera, David A. Hood   +2 more
openaire   +1 more source