Results 161 to 170 of about 2,720 (174)

A Reduction in Tafazzin Decreases Mitochondrial Function in C2C12 Myotubes

The FASEB Journal, 2022
Mitochondria, which are often regarded as the “powerhouse of the cell”, are labile organelles that regulate cellular metabolism, determine cell fate, and act as important signaling hubs. A phospholipid that is exclusively found within mitochondria that serves numerous roles is cardiolipin (CL).
Brandon J. Richards, Ashley N. Oliviera, David A. Hood   +2 more
openaire   +1 more source

Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes

American Journal of Physiology-Heart and Circulatory Physiology, 2010
Mutation of the mitochondrial protein tafazzin causes dilated cardiomyopathy in Barth syndrome. We employed an adenovirus as a vector to transfer tafazzin small hairpin RNA (shRNA) into neonatal ventricular myocytes (NVMs) to investigate the effects of tafazzin knockdown. The tafazzin shRNA adenovirus consistently knocked down tafazzin mRNA and lowered
openaire   +2 more sources

Drosophila Mitochondrial Membrane‐bound Tafazzin Protein Is A Transacylase

The FASEB Journal, 2007
Barth syndrome is an X‐linked mitochondria disorder with skeleton myopathy, cardiomyopathy and neutropenia, resulting from the tafazzin mutation. As demonstrated previously [Xu et al.: PNAS 103:11584, 2006], the mutation of full length Drosophila ...
Yang Xu, Mindong Ren, Ashim Malhotra, Louis Lee, Jin Zhang, Thomas JJ Blanck, Michael Schlame   +6 more
openaire   +1 more source

The role of cardiolipin in molecular assemblies of tafazzin

Mitochondrion, 2011
Ashim Malhotra⁎, Devrim Acehan, Mindong Ren, Michael Schlame   +3 more
openaire   +1 more source

The lipid environment modulates cardiolipin and phospholipid constitution in wild type and tafazzin‐deficient cells

Journal of Inherited Metabolic Disease, 2022
Yvonne Wohlfarter, Stephan Geley, Gregor Oemer   +2 more
exaly  

201 The role of macrophage tafazzin in atherosclerosis

Basic Science
Matthew Batty, Cindy Dong, Anne-Marie Tricolici, Lauren Kitt, Nichola Figg, Martin Bennett, Emma Yu   +6 more
openaire   +1 more source

A linear algebra model of the tafazzin reaction

Chemistry and Physics of Lipids, 2008
openaire   +1 more source

Role of Tafazzin in Mitochondrial Function, Development and Disease

Journal of Developmental Biology, 2020
Simon Conway, Michael Chin, Chin Michael T   +2 more
exaly  

Increased Dynamin‐Related Protein 1–Dependent Mitochondrial Fission Contributes to High‐Fat‐Diet‐Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts

Molecular Nutrition and Food Research, 2019
Jianxun Wang, Wenguang Chang, Mengyang Li   +2 more
exaly  

Mögliche Ursache einer fetalen Herzinsuffizienz: TAFAZZIN-Genvariante

Ultraschall in der Medizin - European Journal of Ultrasound
M. Rehn, E. Kunstmann, P. Paul, D. Schröder, A. Wöckel, U. Pecks   +5 more
openaire   +1 more source