Results 91 to 100 of about 458,059 (348)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The Nameless Shakespeare

open access: yesDigital Studies, 2005
None
Martin Mueller
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Tag Separation in Cardiac Tagged MRI [PDF]

open access: yes, 2008
In this paper we introduce a tag separation method for better cardiac boundary segmentation and tag tracking. Our approach is based on two observations in the cardiac tagged MR images: 1) the tag patterns have a regular texture; 2) the cardiac images without tag patterns are piecewise smooth with sparse gradients.
Junzhou, Huang   +4 more
openaire   +2 more sources

Tagging in Volunteered Geographic Information: An Analysis of Tagging Practices for Cities and Urban Regions in OpenStreetMap

open access: yesISPRS International Journal of Geo-Information, 2016
In Volunteered Geographic Information (VGI) projects, the tagging or annotation of objects is usually performed in a flexible and non-constrained manner. Contributors to a VGI project are normally free to choose whatever tags they feel are appropriate to
Nikola Davidovic   +3 more
doaj   +1 more source

Diacritic Restoration and the Development of a Part-of-Speech Tagset for the Māori Language [PDF]

open access: yes, 2012
This thesis investigates two fundamental problems in natural language processing: diacritic restoration and part-of-speech tagging. Over the past three decades, statistical approaches to diacritic restoration and part-of-speech tagging have grown in ...
Cocks, John
core   +1 more source

An improved neural network model for joint POS tagging and dependency parsing

open access: yes, 2018
We propose a novel neural network model for joint part-of-speech (POS) tagging and dependency parsing. Our model extends the well-known BIST graph-based dependency parser (Kiperwasser and Goldberg, 2016) by incorporating a BiLSTM-based tagging component ...
Nguyen, Dat Quoc, Verspoor, Karin
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Spatial Ecology of the Population of Reef Manta Rays (Mobula alfredi) in New Caledonia Using Satellite Telemetry 2—Vertical Behaviour

open access: yesFishes
In the dynamic and increasingly threatened marine environment, understanding the full spatial ecology of species like the reef manta ray (Mobula alfredi) is crucial for effective conservation.
Hugo Lassauce   +2 more
doaj   +1 more source

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