Results 81 to 90 of about 165,740 (240)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial Ecology of the Population of Reef Manta Rays (Mobula alfredi) in New Caledonia Using Satellite Telemetry 2—Vertical Behaviour

Fishes
In the dynamic and increasingly threatened marine environment, understanding the full spatial ecology of species like the reef manta ray (Mobula alfredi) is crucial for effective conservation.
Hugo Lassauce, Olivier Chateau, Laurent Wantiez   +2 more
doaj   +1 more source

Tagging in Volunteered Geographic Information: An Analysis of Tagging Practices for Cities and Urban Regions in OpenStreetMap

ISPRS International Journal of Geo-Information, 2016
In Volunteered Geographic Information (VGI) projects, the tagging or annotation of objects is usually performed in a flexible and non-constrained manner. Contributors to a VGI project are normally free to choose whatever tags they feel are appropriate to
Nikola Davidovic, Peter Mooney, Leonid Stoimenov, Marco Minghini   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Overview of MediaEval 2011 rich speech retrieval task and genre tagging task [PDF]

, 2011
The MediaEval 2011 Rich Speech Retrieval Tasks and Genre Tagging Tasks are two new tasks oered in MediaEval 2011 that are designed to explore the development of techniques for semi-professional user generated content (SPUG).
Eskevich, Maria, Kofler, Christoph, Schmiedeke, Sebastian, Ordelman, Roeland, Larson, Martha, Jones, Gareth J.F.   +5 more
core   +2 more sources

Reader Responses to Online Reporting of Tagged Bird Behavior

Animals
This paper explores responses to online coverage of an avian tracking project. Researchers attached novel trackers to a small group of wild magpies (Gymnorhina tibicen).
Louise Hayward
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Is big brother watching you? Responding to tagging and tracking in dementia care [PDF]

, 2006
The increased availability of assistive technologies, particularly tagging and tracking technology, raises questions for occupational therapists working in dementia care.
Plastow, N A
core   +2 more sources

Conservation of Native Fishes of the San Francisco Estuary: Considerations for Artificial Propagation of Chinook Salmon, Delta Smelt, and Green Sturgeon

San Francisco Estuary and Watershed Science, 2011
Many native fishes in the San Francisco Estuary and its watersheds have reached all-time low abundances. Some of these declining species (e.g., Chinook salmon Oncorhynchus tschawytscha) have been under artificial propagation for decades. For others (e.g.,
Joshua A. Israel, Kathleen M. Fisch, Thomas F. Turner, Robin S. Waples   +3 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source