Results 91 to 100 of about 2,161,634 (339)

The Economic Implications of Phasing Out Pig Tail Docking: A Pilot Study in Italy

open access: yesAnimals
The European Commission’s ban on routine tail docking has prompted this retrospective observational study to evaluate the short-term effects of transitioning to a fully undocked system. Twenty-two farms were assessed during three subsequent phases: total
Francesca Menegon   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Asymmetric Structure of Podophage GP4 Reveals a Novel Architecture of Three Types of Tail Fibers

open access: hybrid, 2023
Jing Zheng   +6 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Multi-Step Tail Biting Outbreak Intervention Protocols for Pigs Housed on Slatted Floors

open access: yesAnimals, 2019
Solutions are needed to keep pigs under commercial conditions without tail biting outbreaks (TBOs). However, as TBOs are inevitable, even in well managed farms, it is crucial to know how to manage TBOs when they occur.
Jen-Yun Chou   +4 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The Statistical Meaning of Kurtosis and Its New Application to Identification of Persons Based on Seismic Signals

open access: yesSensors, 2008
This paper presents a new algorithm making use of kurtosis, which is a statistical parameter, to distinguish the seismic signal generated by a person's footsteps from other signals. It is adaptive to any environment and needs no machine study or training.
Chunlei Zheng   +6 more
doaj  

Rearing Pigs with Intact Tails—Experiences and Practical Solutions in Sweden

open access: yesAnimals, 2019
Tail biting is a common issue within commercial pig production. It is mainly an indicator of inadequate housing environment and results in reduced health welfare and production.
Torun Wallgren   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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