Results 71 to 80 of about 2,435,177 (387)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
The process of caudal regeneration in lizards does not always occur perfectly, which can cause some abnormalities, such as the appearance of warped or supernumerary tails.
Antônio Rafael Lima Ramos+4 more
doaj +1 more source
Tails of probability density for sums of random independent variables
The exact expression for the probability density $p_{_N}(x)$ for sums of a finite number $N$ of random independent terms is obtained. It is shown that the very tail of $p_{_N}(x)$ has a Gaussian form if and only if all the random terms are distributed ...
A. R. R. Papa+13 more
core +1 more source
Structure of Titan's mid-range magnetic tail: Cassini magnetometer observations during the T9 flyby [PDF]
We analyze the magnetic structure of Titan's mid-range magnetic tail (5-6 Titan radii downstream from the moon) during Cassini's T9 flyby. Cassini magnetometer (MAG) measurements reveal a well-defined, induced magnetic tail consisting of two lobes and a ...
Bertucci, C+7 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Tidal Tails of Minor Mergers: Star Formation Efficiency in the Western Tail of NGC 2782 [PDF]
While major mergers and their tidal debris are well studied, they are less common than minor mergers (mass ratios < 0.3). The peculiar spiral NGC 2782 is the result of a merger between two disk galaxies with a mass ratio of ~4:1 occurring ~200 Myr ago ...
Bigiel+17 more
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Non-asymptotic tails estimations for sums of random vectors having moderate decreasing tails [PDF]
We derive the sharp non-asymptotical uniform estimations for tails of distributions for classical normed sums of centered normed independent random vectors having a moderate decreasing individual tails of summands.
arxiv
A True Human Tail in a Neonate : Case report and literature review
A true human tail is a benign vestigial caudal cutaneous structure composed of adipose, connective tissue, muscle, vessels, nerves and mechanoreceptors.
Mahesh K. Pillai, Smitha T. Nair
doaj +1 more source