Results 91 to 100 of about 2,066,060 (296)

Individual piglets' contribution to the development of tail biting [PDF]

Conflicting hypotheses exist about the contribution of individual pigs to the development of a tail-biting outbreak, but there is limited quantitative information to support or dismiss them.
Bracke, M.B.M., Hartog, L.A., den, Kemp, B., Spoolder, H.A.M., Zonderland, J.J.   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Post-apocalyptic protest, or ideological deformation of the "archetypical family" in the movie "Snowpiercer" / Постапокалиптический протест, или идеологическая деформация «архетипического семейства» в фильме «Сквозь снег»

Индустрии впечатлений: Технологии социокультурных исследований
The article analyzes the film Through the Snow (2013), directed by Pong Jun-ho, as a multi-layered socio-political dystopia that embodies archetypal scenarios of an isolated and simultaneously dynamic post-apocalyptic society. The film's central theme is
Sergey Malenko / Сергей Анатольевич Маленко, Andrey Nekita / Андрей Григорьевич Некита   +1 more
doaj   +1 more source

Morphogenesis of the T4 tail and tail fibers

Virology Journal, 2010
Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components ...
Kanamaru Shuji, Aksyuk Anastasia A, Kostyuchenko Victor A, van Raaij Mark J, Arisaka Fumio, Leiman Petr G, Rossmann Michael G   +6 more
doaj   +1 more source

Faraday Rotation in the Tail of the Planetary Nebula DeHt 5

, 2010
We present 1420 MHz polarization images of a 5x5 degree region around the planetary nebula (PN) DeHt 5. The images reveal narrow Faraday-rotation structures on the visible disk of DeHt 5, as well as two wider, tail-like, structures "behind" DeHt 5 ...
Bally, Bannister, Benedict, Bloecker, Bloecker, Brown, Dauphole, Gray, Han, Harris, Haverkorn, Heiles, Kerber, Landecker, Lawson, M. Wolleben, Matthews, Napiwotzki, Napiwotzki, R. Kothes, R. R. Ransom, Ransom, Reich, Reich, Simmons, Soker, T. L. Landecker, Taylor, Uyanıker, Villaver, Wareing, Wareing, Wareing, Xilouris   +33 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Profile of miRNAs induced during sheep fat tail development and roles of four key miRNAs in proliferation and differentiation of sheep preadipocytes

Frontiers in Veterinary Science
BackgroundThe fat tail of sheep is an adaptive trait that facilitates their adaptation to harsh natural environments. MicroRNAs (miRNAs) have been demonstrated to play crucial roles in the regulation of tail fat deposition.MethodsIn this study, miRNA-Seq
Wei Zhang, Shiyin Wang, Liwei Yang, Li Gao, Chengcheng Ning, Mengsi Xu, Shuangyi Deng, Shangquan Gan   +7 more
doaj   +1 more source

The Dust Tail of Asteroid (3200) Phaethon

, 2013
We report the discovery of a comet-like tail on asteroid (3200) Phaethon when imaged at optical wavelengths near perihelion. In both 2009 and 2012, the tail appears >=350" (2.5x10^8 m) in length and extends approximately in the projected anti-solar ...
Agarwal, Jessica, Jewitt, David, Li, Jing   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source