Results 171 to 180 of about 257,409 (278)

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu   +13 more
wiley   +1 more source

Thermally Regulated Methanol Selectivity in Photo‐Thermo Methane Oxidation Through Interfacial Methyl Transfer

open access: yesAdvanced Science, EarlyView.
Photo‐thermo cascade catalysis enables highly selective methane‐to‐methanol conversion over Au‐ZnO, achieving a CH3OH production rate of ∼800 µmol h−1 with 86% selectivity. Thermal activation gates the transfer of methane‐derived methyl intermediates from ZnO to Au, thereby redirecting the reaction pathway toward methanol formation. ABSTRACT The direct
Youxun Xu   +6 more
wiley   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

open access: yesAdvanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim   +11 more
wiley   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng   +10 more
wiley   +1 more source

The Study of Analgesic Effects of Leonurus cardiaca L. in Mice by Formalin, Tail Flick and Hot Plate Tests. [PDF]

open access: yesInt Sch Res Notices, 2014
Rezaee-Asl M   +4 more
europepmc   +1 more source

3′‐UTR Hypermethylation and ABA Signaling Coordinate Transcriptional Activation of SWEET14 for High Sugar Accumulation in Citrus

open access: yesAdvanced Science, EarlyView.
Hypermethylation of CliSWEET14 3′‐UTR relieves ClibHLH105‐mediated transcriptional repression, together with ABA signaling‐mediated activation of the CliABF3‐CliNAC56 cascade, boosts CliSWEET14 expression and sucrose accumulation in citrus. ABSTRACT Sugar accumulation is pivotal for fruit quality, yet the molecular regulation of this process remains ...
Yike Zeng   +13 more
wiley   +1 more source

SPICE‐Compatible Compact Modeling of Cuprate‐Based Memristors Across a Wide Temperature Range

open access: yesAdvanced Electronic Materials, EarlyView.
A physics‐guided compact model for YBCO memristors is introduced, incorporating carrier trapping, field‐induced detrapping, and a differential balance equation to describe their switching dynamics. The model is compared with experiments and implemented in LTspice, allowing realistic circuit‐level simulations.
Thomas Günkel   +6 more
wiley   +1 more source

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