Results 61 to 70 of about 47,594 (303)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The geochemical features of ores and technosoils of tailing gold-molybdenum mine Davenda in East Transbaikalia

open access: yesЛитосфера, 2016
New data on the mineral and chemical composition of the ore, host rocks and technosoils of tailings gold-molybdenum deposit Davenda are outlined. The mineral composition of the ore (%): quartz (96), molybdenite (1, but on average 0.26), pyrite (7 ...
G. A. Yurgenson   +3 more
doaj   +2 more sources

PENGARUH PENAMBAHAN TOP SOIL INCEPTISOL DAN KOMPOS PADA TAILING AMALGAMASI TERHADAP PANJANG SULUR, DIAMETER SULUR DAN JUMLAH CABANG TANAMAN UBI JALAR (Ipomoea batatas L.)

open access: yesJTSL (Jurnal Tanah dan Sumberdaya Lahan), 2020
Tailings are waste generated from the processing of gold ore. The tailings in Kertajaya Village, Sukabumi are generally dumped into a pond or garden which is then used by the community to grow crops.
Indra Herliana   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Environmental geochemistry of potentially toxic elements in tailing of the Ahangaran Pb-Zn mine, Hamadan province

open access: yesJournal of Economic Geology
The present study aims to investigate the environmental geochemistry of potentially toxic elements (PTEs) in tailing samples of the Ahangaran Pb-Zn mine, located 95 km southeast of Hamadan.
Mahrokh Ghanbari Mohazzab   +2 more
doaj   +1 more source

Impact of the flotation tailing dumps on the living environment of Bor and protective measures [PDF]

open access: yesMining and Metallurgy Engineering Bor, 2013
In the southeastern Serbia, in the area of the municipality Bor, there are three flotation tailing dumps: FTD Bor, FTD RTH (the ore body H) and FTD Veliki Krivelj. The Flotation Tailing Dump Bor is abandoned, partly reclamated.
Lekovski Ružica   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Improvement of Sand Tailing Fertility Derived from Post Tin Mining Using Leguminous Crop Applied by Compost and Mineral Soil [PDF]

open access: yesJournal of Tropical Soils, 2013
The research was aimed to study the potency of two leguminous cover crops in enhancing tailing fertility of post tin mining with and without addition of mineral soil and compost.
Dedik Budianta   +2 more
doaj   +1 more source

Pig tail length is associated with the prevalence of tail malformations but not with inflammation of the tail

open access: yesBMC Veterinary Research
Abstract Background Assuming that tail length is associated with the prevalence of tail biting, attempts are being made to shorten tails by genetic selection in order to avoid the painful procedure of docking. However, undesirable side effects such as kinky tails and inflammatory changes may occur.
Christiane Egerer   +5 more
openaire   +3 more sources

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