Results 111 to 120 of about 33,130 (248)

Sand tailings dams : design, construction and operation

, 2011
The design of sand tailings dams for tailings impoundments in highly seismic regions has been subjected to a long development process with continuous improvement mainly because of the general concern originated by several earthquake induced failures ...
Campaña, Jose, Barrera, Sergio, Valenzuela, Luis   +2 more
core   +1 more source

Filtered dry stacked tailings : the fundamentals

, 2011
Filtered tailings are becoming an increasingly common consideration for tailings management at many mines. There are more filtered dry stack tailings storage facilities than there are surface paste facilities yet the amount of guidance documentation on
Davies, Michael
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Study on permeability characteristics of tailings sand considering particle features

Frontiers in Earth Science
The permeability of the grouting medium is a core parameter determining the grouting effect. To explore the grouting and cementation reinforcement technology for tailings dam faces and improve the toughness of tailings dams against overtopping floods, it
Shuai Xing, Shuai Xing, Jinsheng Jia, Jinsheng Jia, Cuiying Zheng, Cuiying Zheng, Chaojie Wang, Chaojie Wang, Haoxiang Wang, Haoxiang Wang, Yetao Guo, Yetao Guo   +11 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Optimizing dewatering and soft tailings consolidation by enhancing tailings’ composition

, 2015
In order to reclaim ultra-soft tailings (e.g. oil sands) ponds great amount of research and technology work has been performed over the years to optimize the dewatering and consolidation of Fine Fluid Tailings (FFT), including the use of different ...
Sittoni, Luca, Chassagne, Claire, Ibanez, Maria, van Paassen, Leon   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Laboratory Properties of Mine Tailings

, 2001
: A vast amount and variety of mine tailings are produced around the world each day. These mining wastes must be properly managed. To evaluate mine tailings disposal technology, the appropriate engineering properties of the tailings must be ascertained ...
Sego, D. C., Qiu, Y. J.
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source