Results 51 to 60 of about 40,715 (248)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Thirty years of tailings history from Tailings & Mine Waste

, 2011
By virtue of its long-running success, and the many contributed technical papers, the proceedings of the Tailings & Mine Waste and predecessor conferences present a good opportunity to review and consider the progress that has been made in the design ...
Caldwell, Jack A., Van Zyl, Dirk J. A.
core   +1 more source

Performance Comparison between Neutralization Tailings and Flotation Tailings Used for Backfill Mix and Mechanism Analysis

Advances in Materials Science and Engineering, 2016
A comparison test of different tailings used for underground backfill was conducted, using neutralized tailings from BIOX and flotation tailings of Jinfeng Mine.
Bin Han, Wei Sun, Shaofeng Yu, Chao Liu, Song Yao, Jianxun Wu   +5 more
doaj   +1 more source

Kualitas Beton SCC dengan Substitusi Agregat Halus Tailing Tambang Emas Daerah Pongkor

Media Komunikasi Teknik Sipil, 2019
This paper presents the results of self compacting concrete (SCC) with water cement ratio 0.30 with four variations of tailings, ie 0%, 5%, 10% and 15%. Superplastisizer used is a type Naptha 511P of PT.Karya Naptha Belide.
Amalia Amalia, Muhtarom Riyadi
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Extreme Geochemical Conditions and Dispersal Limitation Retard Primary Succession of Microbial Communities in Gold Tailings

Frontiers in Microbiology, 2018
Microbial community succession in tailings materials is poorly understood at present, and likely to be substantially different from similar processes in natural primary successional environments due to the unusual geochemical properties of tailings and ...
Talitha C. Santini, Talitha C. Santini, Maija Raudsepp, Jessica Hamilton, Jasmine Nunn   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Application Status of Iron Tailings in Concrete Preparation

Kuangchan zonghe liyong
[Objective] To address the issues of large-scale iron tailings occupying land and causing environmental pollution, and to achieve efficient and comprehensive utilization of iron tailings, taking iron tailings as the research object, the utilization ...
Yechao ZHENG, Shuang YI, Tonglin ZHAO, Fangyuan MA   +3 more
doaj   +1 more source

Optimization of the effect and formulation of different coarse aggregates on performance of the paste backfill condensation

工程科学学报, 2020
Hydration and setting time of paste-like backfill slurry in the Gansu Province’s Jinchuan copper and nickel mine is slow, and the degree of segregation of coarse aggregate is high, seriously affecting the quality of cemented paste backfill. In this paper,
Sheng-hua YIN, Jia-ming LIU, Wei CHEN, Long ZOU, Yong-yuan KOU, Xi-wen LI   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source