Results 71 to 80 of about 40,715 (248)
De-licensing of Oil Sands Tailings Dams. Technical Guidance Document [PDF]
, 2014 Some of the oil sands tailings dams, licensed under the Alberta dam safety regulations, have reached the end of their service life and under a responsible environmental stewardship should be closed and reclaimed.
Oil Sands Tailings Dam Committee
core +1 more source
Reassessment of best available tailings management practices
, 2015 The way in which tailings are managed reflects the history, the regulatory framework and the environment of the country and locale of the mine. In spite of many attempts to find an environmentally friendly strategy for tailings management that considers ...
Caldwell, Jack +2 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2023 Microbial induced calcite precipitation (MICP) offers a promising solution for a multitude of potential areas of concern with the remediation of mine tailings.
Miles, Sarah M.
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Safety of tailings impoundments: simplified case analysis by Stava 1985 [PDF]
, 2023 openIn questo elaborato verrà descritto in termini generali il tema legato alla produzione di tailings. Verrà inquadrata la problematica che interessa lo stoccaggio di questi materiali e le conseguenze che ne derivano sia termini economici, sia in ...
CAPPELLIN, SIMONE
core
Tailings facility review and evaluation standards
, 2015 Peer review of dams and tailings facilities has been done for a long time. Independent tailings facility review is, however, still not standard practice. This paper describes the authors’ stories of early peer review in which they were involved.
Caldwell, Jack, Robertson, Andrew McG
core +1 more source