Results 61 to 70 of about 40,715 (248)
, 2011 The method of tailings disposal, has a strong influence on the characteristics of the tailings mass within the reservoir and on the behaviour of the tailings dam.
Pimenta de Ávila, Joaquim
core +1 more source
Study on the stability of iron tailings dam improved by curing agent
Frontiers in Earth ScienceFine-grained tailings exhibit poor permeability, prolonged consolidation time, low mechanical strength, and difficulty in dissipating excess pore water pressure.
Shujian Li +11 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Geotechnical risks related to tailings dam operations
, 2011 Tailings dams are geotechnical structures that are increased in height with time. Several factors typical of tailings dams cause a higher risk of failure compared with other earth structures.
List, B. +3 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Optimizing dewatering and soft tailings consolidation by enhancing tailings’ composition
, 2015 In order to reclaim ultra-soft tailings (e.g. oil sands) ponds great amount of research and technology work has been performed over the years to optimize the dewatering and consolidation of Fine Fluid Tailings (FFT), including the use of different ...
Sittoni, Luca +3 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Value-Added Products from Coal Tailings
, 2022 The quantity of coal tailings (CT) currently discharged annually in Qld and NSW is estimated to be between 14 and 16 million dry tonnes with the majority going into tailings storage facilities (TSF).
Jahandari, Soheil (S34960) +9 more
core