Results 61 to 70 of about 33,130 (248)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Investigating the Properties of Foamed Mixture Lightweight Soil Mixed with Bauxite Tailings as Filler

open access: yesAdvances in Materials Science and Engineering, 2019
To make better use of large amounts of discarded bauxite tailings (BTs), a foamed mixture lightweight soil mixed with BTs as filler (FMLSB) was proposed. Using the orthogonal experimental design method, the effects of various contents of cement, BTs, and
Yuansheng Peng   +3 more
doaj   +1 more source

A twist in the tail

open access: yeseLife, 2014
Lipopolysaccharide molecules released by the bacteria Vibrio fischeri when it rotates its flagella prompts its host, the Hawaiian bobtail squid, to prepare for its arrival.
Karen Guillemin, Annah S Rolig
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Experiment research and mechanism analysis on rheological properties of tailings slurry

open access: yesFrontiers in Earth Science, 2023
The particle size and content of tailings are important parameters affecting the rheological properties of tailings slurry. To explore their influence law and mechanism on rheological properties, the experiments of tailings slurry were designed and ...
Zhiliu Wang, Linlin Chen, Mengxin Hu
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reliability-based design of slope angles for spatially varying slopes based on inverse first-order reliability method

open access: yesYantu gongcheng xuebao, 2021
Stability analysis and design of soil slopes are a classic problem in geotechnical engineering. The current commonly-used deterministic analysis (e.g., single factor of safety) approach does not quantify the influences of various uncertainties in slope ...
JIANG Shui-hua 1, 2, LIU Xian 1, 2, HUANG Fa-ming 1, HUANG Jin-song 1, ZHOU Chuang-bing , 2
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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