Results 61 to 70 of about 265,258 (240)

Talent Notice of Adopted Amendment (2008-09-02)

, 2008
10 pp. Adopted 2008-09-02.
Talent (Or.)
core   +1 more source

Crossing Boundaries, Creating Change: A Competence Framework for Bridge-Builders

Baltic Journal of Sport and Health Sciences
Purpose: This study aims to develop a comprehensive competence framework for professionals facilitating cross-sector collaboration, innovation, and systemic change across organisational, disciplinary, and cultural boundaries. It addresses the current gap
Robert Ovbiagbonhia, Carina de Leeuw, Jannet Doppenberg, Jelly Zuidersma   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

An investigation into talent identification and development in English Netball [PDF]

, 2009
The Institute of Sport and Leisure Policy (ISLP) at Loughborough University was pleased to respond to a request by Cathy Partridge, Regional Talent Officer for the East Midlands, and Kelly Parkyn, Talent Manager for England Netball, to investigate talent
Robinson, Leigh, Downward, Paul
core  

B3Emo: Quantifying Affect as a Double-Edged Sword in Strategic LLM Interactions

IEEE Access
The deployment of large language models (LLMs) in interactive roles such as automated negotiators, customer service agents, and strategic partners requires them to handle not only logical tasks but also the socio-emotional dimensions of interaction.
Aleksei Stepin, Mikhail Mozikov, Artyom Kabanov, Vladimir Kubasov, Rustam Akimov, Ivan Nasonov, Nikita Glazkov, Roman Sultimov, Ivan Makovetskiy, Nikita Severin, Yury Maximov, Andrey V. Savchenko, Ilya Makarov   +12 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Talent Notice of Adopted Amendment (2011-05-04) [PDF]

, 2011
42 pp. Adopted 2011-05-04.
Talent (Or.)
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The efficacy of the use of ZiG money as a sole legal tender in Zimbabwe. The case of Chinhoyi Town, Zimbabwe.

The Dyke
To decide on the acceptability and usability of ZiG on the Zimbabwean market, the paper traces the history of the use of the local currencies and the operation of the Reserve Bank of Zimbabwe’s monetary policy dating back to 1980.
Timothy Matinhure, Talent Gwedavi
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source