Results 61 to 70 of about 1,025,126 (312)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Effects of Antisense Oligonucleotides Against miRNA-21 on Growth of Human Colon Cancer Cells in vivo
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the effect of antisense oligonucleotides(ASOs) against miR-21 expression on the growth of human colon carcinoma cells line HCT116 in vivo.
LIU Shiming +5 more
doaj +1 more source
Sustainability and the Talentship Paradigm: Strategic Human Resource Management Beyond the Bottom Line [PDF]
, 2003 [Excerpt] This paper proposes such a framework that simultaneously shifts the prize to reflect Sustainability and shifts the paradigm of HRM toward a decision science called “Talentship” (Boudreau & Ramstad, 2002).
Boudreau, John W.
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Organizational Unlearning: A Bibliometric Study and Visualization Analysis Via CiteSpace
SAGE OpenCoping with evolution and the changes it brings to the workplace remains a major concern for organizational leaders. This study explores the hotspots, trends, and future directions of the field of organizational unlearning to complement the extant ...
Jiang Chen +2 more
doaj +1 more source
, 2012 The battleground of international competitiveness in the 21st century is innovation, and cities are increasingly viewed as the foremost places where innovation takes place.
Leon, Nick
core
Globalization and the Empowerment of Talent [PDF]
, 2003 Lecture on the first SFB/TR 15 meeting, Gummersbach, July, 18 - 20, 2004Globalization has been identified by many experts as a new way firms organize their activities and as the emergence of talent as the new stakeholder in the firm.
Marin, Dalia, Verdier, Thierry
core +7 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Effects of NDUFA4 Overexpression on Growth of Human Colon Cancer Cells in vitro
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the effects of NDUFA4 overexpression on the growth of human colon cancer cells in vitro and to explore its potential mechanism. Methods The recombinant plasmid p-NDUFA4 (p-NDUFA4) and the control plasmid (p-Cont) were transiently
LIU Shiming +7 more
doaj +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source