Results 91 to 100 of about 94,805 (348)

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Practical research on the cultivation of inter-disciplinary undergraduate nursing talents in the context of “big health”

BMC Medical Education
Objective Exploring the construction and effectiveness of a inter-disciplinary undergraduate nursing talent cultivation model in the context of“great health”.
Meichun Tan, Huan Liu, Yingqing Xiang, Lin Xiong, Liqin Zou, Liang Fang   +5 more
doaj   +1 more source

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

Advanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen, Huan Liu, Tengyu Liu, Jie Li, Qizhi Luo, Yan Zhang, Shengkun Li, Hu Li   +7 more
wiley   +1 more source

Quality analysis of soaked bayberry wine prepared by different flavor types Baijiu [PDF]

Zhongguo niangzao
In this study, soaked bayberry wines were prepared by 6 kinds of flavor types (sauce-flavor (Jiangxiangxing), Te-flavor, Chi-flavor, Laobaigan- flavor, light-flavor and strong-flavor (Nongxiangxing)) Baijiu.
SONG Ya, JIN Jiaruo, LIU Yuting, MA Yue, WANG Dian, FENG Xinxin, ZHANG Xu, LI Dong, ZHENG Huayan, YU Shirui
doaj   +1 more source

In Remembrance of Denis Alan Trevor New [PDF]

, 2010
Non
Brent, Robert L, Dr.
core   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Research on the Reform of Talent Training Mode for the Light Chemical Engineering under the Background of New Engineering

Pige Kexue Yu Gongcheng
In order to actively respond to industrial change and the new round of scientific and technological revolution, China's higher engineering education put forward the construction of “new engineering”, which points out the direction for the reform of ...
Xugang DANG, Xuechuan WANG, Xinhua LIU, Huijie ZHANG   +3 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Doctoral Education and Academic Research (in India) [PDF]

, 2006
[Excerpt] The state of doctoral education and academic research in India is poor and the country has scant representation among the world’s great universities. The decline has happened in spite of early achievements.
Chatterjea, Arkadev, Moulik, Satya P
core   +1 more source