Results 71 to 80 of about 14,306 (251)

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

open access: yesAdvanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang   +12 more
wiley   +1 more source

Spatial-Temporal Distribution Characteristics and Influencing Factors of High-Level Tennis Players in China

open access: yesRedai dili
With the vigorous development of the global sports industry and the continuous improvement of competitive sports, the cultivation and development of sports talent has become an important component of sports strategies in various countries.
Chen Kunlun   +3 more
doaj   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen   +6 more
wiley   +1 more source

Synergized Tri‐Phase Anode via Purposive Ba2+ Doping at the La3+ Site in LaFe0.7Ni0.3O3‐δ for Improved SOFC Performance

open access: yesAdvanced Science, EarlyView.
Purposive doping of low electronegative Ba2+ (0.89) at La3+ (1.1) site in LaFe0.7Ni0.3O3‐δ induces the formation of a tri‐phase composite, which shortens Fe─O bond and lowers activation energy, thereby significantly improves electrical conductivity and catalytic activity, and finally offers a record‐high peak power density in La0.5Ba0.5Fe0.7Ni0.3O3‐δ ...
Qian Yang   +11 more
wiley   +1 more source

Talent cultivation in health technology assessment: an expert survey. [PDF]

open access: yesBMC Med Educ, 2022
Wu YS, Chen C, Wang LC, Jian LS, Ko Y.
europepmc   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun   +19 more
wiley   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu   +14 more
wiley   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

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