Results 231 to 240 of about 553,959 (357)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Beyond chronological age: maturity offset is positively associated with performance in throwing-related tests in youth track and field throwing athletes. [PDF]

Front Sports Act Living
Severin J, Nolte S, Abel T, Schapschröer M.   +3 more
europepmc   +1 more source

Research on Engineering Leading Talents Training Model [PDF]

Proceedings of the 2018 4th Annual International Conference on Modern Education and Social Science (MESS 2018), 2018
Wei-Gong LV, Jian-Xiong LI, Dian-Hui CHU, Jia-Nan JIANG, Song-Lin GU, Ce ZHANG   +5 more
openaire   +1 more source

“Menswear Structure and Technology” Course Based on Application-oriented Talent Training Reform Exploration [PDF]

L Wang, Li Zhao, Yunjuan Liu
openalex   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Investigating the coach's eye when evaluating and selecting 3 × 3 basketball players. [PDF]

Front Psychol
Cermak N, Koopmann T, Siebert L, Schorer J, Zentgraf K.   +4 more
europepmc   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Exploring "Talent" in Medical Education: A Scoping Review. [PDF]

Perspect Med Educ
Preyra R, Mishra S, Khan H, Saha S, Dhillon A, Keuhl A, Monteiro S, Wooster EM, Gottlieb M, Peever A, Chan TM.   +10 more
europepmc   +1 more source

Analysis on the Challenges and Countermeasures of Talent Training in Higher Vocational Education

, 2020
Lin Lv
openalex   +2 more sources

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source