Results 101 to 110 of about 1,573,132 (324)
Diagnostic PathologyA 43-year-old man with sigmoid colon adenocarcinoma (low-grade, moderately) developed multiple pulmonary metastases, presenting an unusual immunohistochemical profile. Histologically, resected lung nodules showed metastatic adenocarcinoma consistent with
Nhu Tung Tran +4 more
doaj +1 more source
Smooth (non)rigidity of piecewise rank one locally symmetric manifolds
, 2011 We define \emph{piecewise rank 1} manifolds, which are aspherical manifolds that generally do not admit a nonpositively curved metric but can be decomposed into pieces that are diffeomorphic to finite volume, irreducible, locally symmetric, nonpositively
Phan, T. Tam Nguyen
core +1 more source
Advanced Science, EarlyView.Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li +12 more
wiley +1 more source
The Construction of the Past: Towards a Theory for Knowing the Past
Information, 2019 This paper presents Constructed Past Theory, an epistemological theory about how we come to know things that happened or existed in the past. The theory is expounded both in text and in a formal model comprising UML class diagrams.
Kenneth Thibodeau
doaj +1 more source
Journal of Hematology & Oncology, 2019 BackgroundTumor microenvironment (TME) is a complex environment containing tumor cells, tumor-associated macrophages (TAMs), interstitial cells, and non-cellular components.
Xiaobin Lin +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Journal of Translational MedicineCancer cells orchestrate the surrounding tumor microenvironment (TME) to strike a fine balance between tissue regeneration providing them with nutrients, and tissue destruction triggered by immunogenic alarm signals.
Salvatore De Rosis +7 more
doaj +1 more source
Arthroscopy TechniquesThe evidence to date still favors anterior cruciate ligament (ACL) reconstruction over anterior cruciate ligament repair because ACL repair has a higher failure rate.
Nguyen Quang Ton Quyen, M.D. +4 more
doaj +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Arthroscopy TechniquesThe number of anterior cruciate ligament (ACL) ruptures treated arthroscopically has increased. In most cases, the rupture of the ligament occurs in the femoral attachment, leaving a robust stump attached to the tibia.
An Van Duy Ho, M.Sc., M.D. +4 more
doaj +1 more source