Results 161 to 170 of about 1,573,132 (324)

Targeting <i>SPP1</i> ⁺TAMs associated with liver metastasis reverses immunosuppression and synergizes with immunotherapy in colorectal cancer. [PDF]

J Immunother Cancer
Lin Y, Chen Z, Zhao S, Zhao L, Yang C, Zhu M, Ye Y, Wang S, Shen Z.   +8 more
europepmc   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Long-term tamoxifen impacts the ovary but not preimplantation embryo development†. [PDF]

Biol Reprod
Kutlutürk GZ, Place TL, Awadalla MS, Danis RB, Ingles SA, Asante I, Li R, Louie S, Stanczyk FZ, McGinnis LK.   +9 more
europepmc   +1 more source

Real‐Time In Vivo Visualization of Tumor‐Associated Macrophage Reprogramming Using a Nitric Oxide‐Activatable NIR‐II Nanoinducer

Advanced Science, EarlyView.
Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen, Meng Li, Tuanwei Li, Chen Yang, Xiaohu Yang, Hongchao Yang, Yejun Zhang, Chunyan Li, Qiangbin Wang   +8 more
wiley   +1 more source

Exploring Vietnamese Students' Intention to Adopt AI-Powered Study Tools: Integrating TPB and TAM

Educational Process: International Journal
Background/purpose. The study addresses the lack of clear policies and ethical concerns surrounding AI use in Vietnamese universities, where debates continue over balancing AI’s benefits with risks of academic misconduct.
Thanh Huong Nguyen , Do Anh Tu Ha
doaj   +1 more source

How Does Transcription-Associated Mutagenesis Shape tRNA Microevolution? [PDF]

Genome Biol Evol
Baños H, Wang L, Simonti C, Paaby AB, Heitsch C.   +4 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Targeting Tumor-Associated Macrophages and Cancer-Associated Fibroblasts to Overcome Therapeutic Resistance in Hepatocellular Carcinoma. [PDF]

Clin Cancer Res
Cho HJ, Kwon M, Varner JA.
europepmc   +1 more source

Quo vadis TAM?

Journal of the AIS, 2007
Izak Benbasat, Henri Barki
semanticscholar   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source