Results 141 to 150 of about 318,382 (250)

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Development of a defatting strategy to reduce lipid accumulation and improve the viability of steatotic grafts in liver transplantation

Annals of Hepatology, 2020
A. Casillas-Ramírez, A.Y. Rocha-Sánchez, Y.E. Hernández-Olvera, K.Y. Balderas-Osorio, H.Y. Martínez-Padrón, C.A. Barrón-Vargas, P. Cordero-Pérez, H.A. Zapata-Chavira   +7 more
doaj   +1 more source

Hidden in plain sight: a maize 'PAL' with aminomutase activity. [PDF]

Plant J
Wood C.
europepmc   +1 more source

Tam Tam in je broekzak

, 2012
Dit is het eindverslag van de stage "Tam Tam in je broekzak", die wij hebben uitgevoerd in het kader van IN3405 Bachelorproject. Deze stage is uitgevoerd bij Tam Tam B.V.
Van Graafeiland, B. (author), Ngai, W.L. (author), Jagesser, A.S. (author)   +2 more
core  

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Dual roles of renal tubular mitochondrial Akt1 in protecting against diabetic nephropathy and improving body glucose metabolism. [PDF]

J Endocrinol
Salem ESB, Ta A, Bloom-Saldana E, Fueger PT, Wang PH.   +4 more
europepmc   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Traditional Chinese medicine modulates tumor-associated macrophages to suppress gastric cancer progression: mechanisms and therapeutic potential. [PDF]

Front Oncol
Zhuang X, Yang Q, Huang L, Liu R, Ma T, Guan L, Zheng Y.   +6 more
europepmc   +1 more source

Le Tam-Tam

, 1872
Variante(s) de titre : Le Tam-tam : hebdomadaire, politique, satirique ...

core  

Perceived GenAI competency and university teachers' intention to continue using generative artificial intelligence: Extending the technology acceptance model. [PDF]

PLoS One
Wang Q.
europepmc   +1 more source