Results 61 to 70 of about 106,118 (266)

Macrophage‐to‐Myofibroblast Transdifferentiation Contributes to Pulmonary Fibrosis via the MERTK‐SPP1‐SRC‐TKS5 Signaling Axis

open access: yesAdvanced Science, EarlyView.
MERTK is upregulated in fibrotic macrophages and regulates the expression and activity of SRC and TKS5 through SPP1, mediating transdifferentiation of macrophages‐to‐myofibroblasts (MMT) and promoting pulmonary fibrosis. The figure was created with BioRender.com.
Yungeng Wei   +3 more
wiley   +1 more source

Aberrant TTF-1 expression in metastatic colorectal adenocarcinoma mimicking primary lung cancer: a case report and review of diagnostic pitfalls

open access: yesDiagnostic Pathology
A 43-year-old man with sigmoid colon adenocarcinoma (low-grade, moderately) developed multiple pulmonary metastases, presenting an unusual immunohistochemical profile. Histologically, resected lung nodules showed metastatic adenocarcinoma consistent with
Nhu Tung Tran   +4 more
doaj   +1 more source

Double-Bundle Anterior Cruciate Ligament Repair and Augmentation With Lateral Extra-articular Tenodesis

open access: yesArthroscopy Techniques
The evidence to date still favors anterior cruciate ligament (ACL) reconstruction over anterior cruciate ligament repair because ACL repair has a higher failure rate.
Nguyen Quang Ton Quyen, M.D.   +4 more
doaj   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang   +10 more
wiley   +1 more source

Remnant Preservation Anterior Cruciate Ligament Reconstruction: Modified All-Inside Technique With Appendiceal Tibial Tunnel

open access: yesArthroscopy Techniques
The number of anterior cruciate ligament (ACL) ruptures treated arthroscopically has increased. In most cases, the rupture of the ligament occurs in the femoral attachment, leaving a robust stump attached to the tibia.
An Van Duy Ho, M.Sc., M.D.   +4 more
doaj   +1 more source

Nilai-Nilai Budaya Dalam Tam Tam

open access: yesMudra Jurnal Seni Budaya, 2019
Tam Tam merupakan karya sastra Bali tradisional berbentuk geguritan. Geguritan memiliki sistem konvensi yang khas, yakni menggunakan pupuh. Setiap pupuh memiliki fungsi, dani padalingsa. Dalam tulisan ini, Geguritan Tam Tam dijadikan objek penelitian.
openaire   +3 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

Esophageal achalasia compressing the left atrium and mimicking an extracardiac tumor on the transthoracic echocardiography: A case report

open access: yesRadiology Case Reports
Achalasia is an uncommon disorder affecting esophageal motility. Occasionally, the appearance of a dilated esophagus in achalasia may resemble an extracardiac tumor when observed through transthoracic echocardiography.
Khoa Le, MD   +5 more
doaj   +1 more source

Drivers of Pre-service and In-service Teachers’ Acceptance and Integration of Emerging Technologies into Pedagogical Practices [PDF]

open access: yesEducaţia 21
The rate of development of educational technologies has implications not only for the technical capacity of an educational institution to provide hardware and software solutions for the existing learning environment, but also for pedagogical practices ...
Nadia Barkoczi   +2 more
doaj   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang   +9 more
wiley   +1 more source

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