Results 151 to 160 of about 1,834 (288)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Security enhancement using scalable Blockchain-based Multi-Factor Authentication (BMFA). [PDF]

PLoS One
Rahman F, Fatima A, Hassan M, Al-Zyoud M, Alfaidi A, Maktoof MAJ, Ghazal TM.   +6 more
europepmc   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

British Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu, Zengbing Lu, Julia Yuen Hang Liu, Man Piu Ngan, Kai‐Hei Tse, John Anthony Rudd   +5 more
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Survey on Visualization of Information Diffusion over Networks

Computer Graphics Forum, EarlyView.
Abstract Information Diffusion (ID) describes how a value (e.g., a pathogen, a rumor, a packet) spreads through an underlying “medium” network of elements (e.g., a social or computer network). Understanding the information diffusion process is essential to predicting trends, controlling misinformation, and enhancing decision‐making as well as ...
T. Baumgartl, M. Sondag, V. Filipov, M. Tuscher, S. Rajendran, S. Miksch, D. Archambault, A. Arleo, T. von Landesberger   +8 more
wiley   +1 more source

Towards Secure Embodied Communication Management in AI Era: Reputation-Guided Agent Message Exchange. [PDF]

Sensors (Basel)
Mu J, Wan L, Dong Z, Wei Y, Xu Z.
europepmc   +1 more source

Evaluating synthetic substitutes to reduce illegal harvesting and support species recovery

Conservation Biology, EarlyView.
Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened species. Yet, there is little evidence on whether product substitution prevents illegal or unsustainable harvesting and contributes to the recovery of threatened populations.
Aditya Shekhar Malgaonkar, Gareth Whittington‐Jones, Tristan Dickerson, Maswabi Lishandu, Sarah Davies, Zoe Woodgate, Xia Stevens, Choolwe Mulenga, Gift Mulenga, Mathew Phiri, Lucky Mulenga, Manyando Mukela, Gryton Kasamu, Willem A. Nieman, Gareth Mann, Abishek Harihar, Diogo Veríssimo, Rob Pickles   +17 more
wiley   +1 more source

A Blockchain-Based Framework With Zero-Knowledge Proof Incorporated for Safeguarded Sharing of Genomic Data Through Health Record Systems. [PDF]

Blockchain Healthc Today
Krishappa N, Shivappa GG, Zachariah S, Thanushree, Pattan KI, Paria A, Hiremath S, Vaithiyanathan R.   +7 more
europepmc   +1 more source

Declining female participation: Mechanisms at play in the Viennese private annuity market, c. 1360–1450

The Economic History Review, EarlyView.
Abstract During the high and late Middle Ages, the European economy witnessed the emergence and substantial growth of capital markets, a phenomenon connected to urbanization and pestilence, both of which brought profound changes to the social, legal, and economic positions of women.
Anna Molnár
wiley   +1 more source

Phase-Changing Vanadium Oxides for Electromagnetic Radiation Management. [PDF]

Small Sci
Taha M, Daeneke T, Walia S.
europepmc   +1 more source