Results 181 to 190 of about 7,520 (210)
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Tamsulosin for benign prostatic hyperplasia
Cochrane Database of Systematic Reviews, 2002Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate which can result in bothersome lower urinary tract symptoms. The treatment goal for men with BPH is to relieve these bothersome symptoms.This systematic review assessed the effects of tamsulosin in the treatment of lower urinary tract symptoms (LUTS) compatible with BPH ...
Indy Rutks +2 more
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Metabolism of tamsulosin in rat and dog
Xenobiotica, 19961. The metabolism of tamsulosin hydrochloride (TMS), a potent alpha 1-adrenoceptor blocking agent, was studied after a single oral administration to rat and dog. 2. Eleven metabolites (1, 2, 3, 4 and their glucuronides, sulphates of 1 and 3, and A-1) were identified from the urine and bile of rat and dog administered TMS. 3.
H. Matsushima +5 more
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Tamsulosin for voiding dysfunction in women
International Urology and Nephrology, 2012Lower urinary tract symptoms (LUTS) affect countless individuals worldwide with an increased prevalence among those≥60 years of age. As the world's population ages, the prevalence of LUTS will continue to increase, diminishing the quality of life of many men and women. For men, alpha-1-adrenergic receptor (α1-AR) blockers are used as first-line therapy
Laura E. Meyer, Jamie N. Brown
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Priapism Following Ingestion of Tamsulosin
Journal of Urology, 2003While priapism has been noted rarely in patients taking -adrenergic blocking agents, including doxazosin, terazosin and prazosin, to our knowledge we report the first detailed case of priapism following ingestion of tamsulosin.1, 2 CASE REPORT A 58-year-old Hispanic male presented with painful priapism 7 hours in duration.
Scott R. Serels +2 more
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The Journal of Clinical Pharmacology, 2008
The tolerability of dapoxetine, a short‐acting selective serotonin reuptake inhibitor being developed for premature ejaculation, was evaluated when coadministered with tamsulosin. Adult men on a stable dose of tamsulosin were randomized to also receive dapoxetine 30 or 60 mg, or placebo, in a crossover design.
Joseph W. Aquilina +3 more
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The tolerability of dapoxetine, a short‐acting selective serotonin reuptake inhibitor being developed for premature ejaculation, was evaluated when coadministered with tamsulosin. Adult men on a stable dose of tamsulosin were randomized to also receive dapoxetine 30 or 60 mg, or placebo, in a crossover design.
Joseph W. Aquilina +3 more
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New practical synthesis of Tamsulosin
Chirality, 2008AbstractThe medicine called Tamsulosin was produced 25 years ago and since then almost 10 new synthesis route has been known. Each process shows the researchers' workstyle, every year, which mainly differs in the way of separating the enantiomers. The applied reaction steps also reflect the development over the past 25 years and the new synthesis is ...
T. Gizur +6 more
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Is Tamsulosin Linked to Dementia in the Elderly?
Current Urology Reports, 2018Lower urinary tract symptoms (LUTS) result from age-related changes in detrusor function and prostatic growth that are driven by alterations in the ratio of circulating androgens and estrogens. Alpha-adrenergic receptor blockers are commonly used to treat LUTS because they influence urethral tone and intra-urethral pressure.
Jason Frankel +2 more
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Drugs & Aging, 2012 The 5α-reductase inhibitor dutasteride and the α(1)-adrenergic receptor antagonist tamsulosin are available as a fixed-dose combination for use in men with symptomatic benign prostatic hyperplasia (BPH) and an enlarged prostate. Dutasteride 0.5 mg/day plus tamsulosin 0.4 mg/day improved lower urinary tract symptoms (LUTS) to a significantly greater ...
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European Urology Supplements, 2007
Abstract The present paper discusses the consequences of nocturia in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) and summarises the available data on the impact of tamsulosin oral controlled absorption system (OCAS) on nocturia.
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Abstract The present paper discusses the consequences of nocturia in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) and summarises the available data on the impact of tamsulosin oral controlled absorption system (OCAS) on nocturia.
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Intraoperative floppy iris syndrome associated with tamsulosin [PDF]
Journal of Cataract and Refractive Surgery, 2005 To assess the incidence and possible causative factors of a newly recognized syndrome, the intraoperative floppy iris (IFIS).Clinical practices in Los Altos and San Rafael, California, USA.A retrospective chart review of consecutive cataract surgeries performed in a 2-surgeon practice over a 12-month period (706 eyes; 511 patients) was used to assess ...
John R. Campbell, David F. Chang
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