Results 71 to 80 of about 6,841 (195)

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Tamsulosin oral controlled absorption system (OCAS) in the treatment of benign prostatic hypertrophy

, 2008
Mischel G Neill, Rohan Shahani, Alexandre R ZlottaDivision of Urology, Department of Surgical Oncology, Princess Margaret and Mount Sinai Hospitals, University of Toronto, Toronto, CanadaAbstract: The efficacy of tamsulosin at the cost of a relatively ...
Mischel G Neill, Alexandre R Zlotta, Rohan Shahani   +2 more
core  

A first case of fixed drug eruption due to Tamsulosin

, 2020
Background: Fixed Drug Eruption (FDE) is a drug reaction involving the skin and less commonly the mucosal membranes. Tamsulosin is an alpha-1 adrenergic receptor blocker used to treat benign prostatic hyperplasia.
Nouripour, B., Ahmadi, A., Jahani Amiri, K., Montazer, F., Mofarrah, R.   +4 more
core  

A comparative study of efficacy and safety of tamsulosin with nifedipine versus tamsulosin alone as medical expulsive therapy for lower ureteric stones

, 2019
Background: Lower ureteric stones (LUS) comprises of 70% of ureteric stones. Spontaneous passage depends on stone size and location in ureter. Impacted calculi initiate smooth muscles contractions causing ureteric spasms. α-1 blockers like tamsulosin and
Sanji, Narendranath, Hanumanthareddy, Shashikala Gowdara, Suresh, Arun, Nagarajappa, Naveen Hebbal, Kamath, Pallavi Mahadeva   +4 more
core   +1 more source

Efficacy and Safety of Vibegron Add‐On Therapy for Persistent Overactive Bladder Symptoms in Benign Prostatic Hyperplasia Patients With α1‐Blocker Treatment: A Multi‐Center Prospective Randomized Controlled Study (VATON Study)

LUTS: Lower Urinary Tract Symptoms, Volume 18, Issue 2, March 2026.
ABSTRACT Objectives To evaluate the efficacy and safety of vibegron add‐on therapy for persistent overactive bladder (OAB) symptoms after α1‐blocker monotherapy for benign prostatic hyperplasia (BPH). Methods Eligible patients were aged ≥ 50 years and diagnosed with BPH.
Masaki Yoshida, Yoshinori Nishino, Hiroshi Nagae, Shinobu Kato, Sadaaki Sakamoto, Morifumi Hojo, Toshihide Miyauchi, Shinji Kageyama, Shinichi Takahashi, Hideya Kuroda, Naoki Mori, Yasuhiro Kasagi, Koichi Masunaga, Yoshiyuki Nabeshima, Masanori Nomiya, Koichi Iwashita, Koichi Miyamae, Masayuki Otani, Kazuya Kawahara, Makoto Ikeda, Shinichi Kubono, Nobuhiro Haga   +21 more
wiley   +1 more source

Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate

, 2009
J Miller, TH TarterSouthern Illinois University School of Medicine, Department of Surgery, Springfield, IL, USAAbstract: Benign prostatic hyperplasia (BPH) is a frequent cause of lower urinary symptoms, with a prevalence of 50% by the sixth decade of ...
J Miller, TH Tarter
core  

LONG-TERM ADMINISTRATION OF TAMSULOSIN INCREASE APOPTOSIS ON PROSTATE CELL OF BPH PATIENT: STUDY ON TGF-ß1, SMAD-4, AND NF- KB

Jurnal Urologi Indonesia
Objective: In this study we aimed to know further mechanism and relation between the long-term usage of tamsulosin with the apoptotic mechanism on prostatic cells of BPH patients qualitatively.
Faathir Baihaqi Ghifary, Besut Daryanto, Karyono Mintaroem   +2 more
doaj   +1 more source

TAMSULOSIN OR SOLIFENACIN IN LUTS PATIENTS DUE TO DJ-STENT INSERTION

Jurnal Urologi Indonesia, 2013
Objective: To evaluate the efficacy of tamsulosin or solifenacin for treatment of Lower Urinary Tract Symptoms (LUTS) due to an indwelling ureteral stent.
Subkhan Subkhan, Tarmono Djojodimedjo, Lukman Hakim, Budiono Budiono   +3 more
doaj   +1 more source

Incidence, clinical findings and management of intraoperative floppy iris syndrome associated with tamsulosin

, 2009
To determine the risk ratios and incidence of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients using tamsulosin, and to assess management strategies for IFIS.
Karahan, Mine, Kaan Unlu, Yusuf Celik, Keklikci, Ugur, Celik, Yusuf, Unlu, Kaan, Isen, Kenan, Ugur Keklikci, Kenan Isen, Mine Karahan   +9 more
core   +1 more source