Results 51 to 60 of about 10,659 (202)

The Determinants of Negotiated Pharmaceutical Prices

The Journal of Industrial Economics, EarlyView.
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert, Sebastian Linde, Brandon Norton   +2 more
wiley   +1 more source

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, Volume 86, Issue 8, Page 891-899, June 2026.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Uroselective α1A-Adrenoceptor Antagonist Tamsulosin in Treatment Lower Urinary Tract Symptoms in Men with Benign Prostatic Hyperplasia

Российский журнал гериатрической медицины
Lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) is a common condition in older man. Uroselective a1a-adrenoceptor (AR) antagonists tamsulosin and tamsulosin modified release (OCAS) are the most frequently prescribed ...
G. G. Krivoborodov, N. S. Efremov, D. A. Shirin, A. A. Gontar, O. N. Tkacheva   +4 more
doaj   +1 more source

SUCCESS RATES OF TAMSULOSIN AND DUTASTERIDE AS MEDICAL THERAPY BASED ON IPSS IN SYMPTOMATIC BPH PATIENTS IN ARIFIN ACHMAD HOSPITAL PEKANBARU RIAU

Jurnal Urologi Indonesia, 2018
Objective: To evaluate the success rates of tamsulosin and dutasteride as medical therapy based on international prostate symptom score (IPSS) in symptomatic benign prostatic hyperplasia (BPH) patients. Materials & Methods: We reviewed medical records of 
Zuhirman Zamzami
doaj   +1 more source

Bedside risk score for medical therapy failure in small‐volume BPH: Temporal validation

BJUI Compass, Volume 7, Issue 5, May 2026.
Abstract Purpose Medical therapy is the first‐line treatment for lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). However, predictors of treatment failure in men with small prostate volume (<30 ml) remain poorly defined.
Numan Alam, Naveed Ahmad, Syed Hamzah Shirazi, Aftab Ahmed, Bilal Suria, Jamahid Ali, Muhammad Anas Ghazi, Elham Shenawa, Mirza Muhammad Hadeed Khawar   +8 more
wiley   +1 more source

α1A Adrenoreceptor blockade attenuates myocardial infarction by modulating the integrin-linked kinase/TGF-β/Smad signaling pathways

BMC Cardiovascular Disorders, 2023
Background Myocardial infarction (MI) is considered a public health problem. According to the World Health Organization, MI is a leading cause of death and comorbidities worldwide. Activation of the α1A adrenergic receptor is a contributing factor to the
Nawal M. Alrasheed, Raghad B. Alammari, Tahani K. Alshammari, Maha A. Alamin, Abeer O. Alharbi, Asma S. Alonazi, Anfal F. Bin Dayel, Nouf M. Alrasheed   +7 more
doaj   +1 more source

PENGARUH PENGOBATAN TAMSULOSIN TERHADAP FUNGSI EREKSI PADA PASIEN BENIGN PROSTATIC HYPERPLASIA [PDF]

, 2015
Benign Prostatic Hyperplasia (BPH) sering ditemukan pada orang lanjut usia begitu juga dengan disfungsi ereksi (DE). Salah satu pengobatan BPH berdasarkan Pedoman Penatalaksanaan BPH di Indonesia adalah Tamsulosin.
Harjuna Muhammad
core  

From “Passive Supplementation” to “Active Repair”: Melatonin Reshapes the Treatment Paradigm for Late‐Onset Hypogonadism by Targeting Leydig Cell Senescence

Aging Cell, Volume 25, Issue 5, May 2026.
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu, Gang Ning, Mintao Jian, Ajian Peng, Haoyu Wang, Bonan Li, Xing Zhou   +6 more
wiley   +1 more source

The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms [PDF]

, 2009
Background The purpose of the current study was to validate the US English Patient Perception of Study Medication (PPSM) questionnaire, which measures patient satisfaction with Benign Prostatic Hyperplasia (BPH) treatment and was administered to men with
Libby Black, Alyson Grove, Betsy Morrill
core   +1 more source

Metastatic Prostate Cancer Masquerading as Locally Advanced Breast Cancer

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT We report a rare case of a 72‐year‐old man with prostatic adenocarcinoma metastasizing to gynecomastia breast tissue with ipsilateral axillary lymph node involvement. This presentation is notable for the absence of disseminated metastatic disease or prolonged androgen deprivation therapy.
Tess Howard, Mylestone Gobe Monna, Jasmine Zhu, Jiasian Teh, Sze Ting Lee, Grace L Chew   +5 more
wiley   +1 more source