Results 41 to 50 of about 10,659 (202)

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Clinical use of the beta-3 adrenoceptor agonist mirabegron in patients with overactive bladder syndrome [PDF]

open access: yes, 2015
Mirabegron is a β 3 adrenoceptor agonist licensed for the treatment of overactive bladder symptoms, such as urinary urgency or urgency incontinence. β 3 adrenoceptor activation causes detrusor muscle relaxation, but mirabegron may also act by binding ...
Drake, Marcus, Vij, Monika
core   +2 more sources

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

Tamsulosin � turn a round [PDF]

open access: yes, 2011
Tamsulosin is a sulfamoylphen-ethylamine derivative, a potent and a selective antagonist of Alpha-1A adrenoceptor. It s approved in the treatment of LUTS in BPH disease, being a specific Alpha -1A blocker it does not interfere much with the ...
Praveen R, Int J Cur Bio Med Sci.
core  

Does the addition of Serenoa repens to tamsulosin improve its therapeutical efficacy in benign prostatic hyperplasia? [PDF]

open access: yes, 2013
Background/Aim. It has been observed that a large number of patients with low urinary tract symptoms due to benign prostatic hyperplasia (LUTS/BPH)) has been treated with a combination of tamsulosin (TAM) + Serenoa repens (SR) (TAM + SR).
Argirović Aleksandar   +1 more
core   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Body Weight Determination and Histological Examination of Livers in Normal Rats Administered with Tamsulosin

open access: yesJournal of Applied Sciences and Environmental Management, 2020
The objective of this study was to investigate histopathology of livers and carry out body weight determination in normal rats administered with  tamsulosin. Standard methods and procedures were used in this study. The results were revealed.
M. Dikko, Y. Sarkingobir
doaj   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye   +18 more
wiley   +1 more source

Free combination of dutasteride plus tamsulosin for the treatment of benign prostatic hyperplasia in South Korea: analysis of drug utilization and adverse events using the National Health Insurance Review and Assessment Service database

open access: yesBMC Urology, 2021
Objective To assess the use and safety of free combination therapy (dutasteride and tamsulosin), dutasteride monotherapy, or tamsulosin monotherapy in patients with benign prostatic hyperplasia (BPH).
Zrinka Lulic   +9 more
doaj   +1 more source

The efficacy of mirabegron additional therapy for lower urinary tract symptoms after treatment with α1-adrenergic receptor blocker monotherapy: prospective analysis of elderly men [PDF]

open access: yes, 2016
BACKGROUND: Mirabegron is a β3-adrenoreceptor agonist developed for treatment of overactive bladder (OAB). α1-Adrenergic receptor blockers are effective for lower urinary tract symptoms (LUTS) in male patients.
Akihiro Asai   +6 more
core   +1 more source

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