Results 121 to 130 of about 12,699,384 (343)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
The TanDEM-X Acquisition Timeline and Mission Plan [PDF]
, 2008 This paper introduces the TanDEM-X data acquisition plan that fulfils the requirements of deriving a global DEM according to the emerging HRTI-3 quality standard within three years mission time. Therefore, a joint TerraSAR-X and TanDEM-X data acquisition
Zink, Manfred +4 more
core
Large Along-Track Baseline SAR-GMTI: First Results With The TerraSAR-X/TanDEM-X Satellite Constellation [PDF]
, 2011 In the paper first ground moving target indication (GMTI) and parameter estimation results obtained with the spaceborne TerraSAR-X/TanDEM-X satellite constellation are presented and discussed.
Baumgartner, Stefan V. +3 more
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Quality assessment of TanDEM-X Raw DEMs oriented to a fusion with CartoSAT-1 DEMs [PDF]
, 2013 This paper addresses a quality assessment of TanDEM-X standard Raw DEMs, with a resolution of 12 meters, for three different terrain configurations: urban areas, moderate topography and complex topography.
Reinartz, Peter +4 more
core
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
A Tandem TerraSAR-X Configuration for Single-Pass SAR Interferometry [PDF]
, 2004 TanDEM-X is a mission proposal for a TerraSAR-X add-on satellite to enable high-resolution single-pass SAR interferometry. The TanDEM-X mission has the goal of generating a global Digital Elevation Model (DEM) with an accuracy corresponding to the DTED-3
Werner, Marian +7 more
core
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Remote Sensing, 2018 Space-based Interferometric Synthetic Aperture Radar (InSAR) applications have been widely used to monitor the cryosphere over past decades. Owing to temporal decorrelation, interferometric coherence often severely degrades on fast moving glaciers ...
Sang-Hoon Hong +5 more
doaj +1 more source
TanDEM-X: A Global Mapping Mission [PDF]
, 2008 TanDEM-X (TerraSAR-X Add-on for Digital Elevation Measurements) is a bistatic SAR interferometry mission which is currently implemented as a national Earth observation mission by the German Aerospace Center (DLR) and EADS Astrium GmbH.
Zink, Manfred +5 more
core