Results 111 to 120 of about 12,254,723 (343)
Mapping Retrogressive Thaw Slumps Using Single-Pass TanDEM-X Observations
Vast areas of the Arctic host ice-rich permafrost, which is becoming increasingly vulnerable to terrain-altering thermokarst in a warming climate. Among the most rapid and dramatic changes are retrogressive thaw slumps.
Philipp Bernhard +3 more
semanticscholar +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The estimation of the volume of volcanic flows during an ongoing eruption is challenging but this information is crucial for improving risk assessment and for forecasting future events.
F. Albino +6 more
semanticscholar +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
TanDEM-X Scientific Results and Future Formation Flying SAR Missions [PDF]
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was launched on June 21, 2010. This paper gives an overview of scientific experiments that have been conducted during the TanDEM-
Lopez Dekker, Paco +9 more
core
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
TanDEM-X Mission: Overview and Evaluation of intermediate Results [PDF]
The German Aerospace Center (DLR, Deutsches Zentrum für Luft- und Raumfahrt) currently conducts the bistatic interferometric synthetic aperture radar (SAR) Mission TanDEM-X, which shall result in a DEM of global coverage in an unprecedented resolution ...
U. Soergel, K. Jacobsen, L. Schack
doaj +1 more source
Continental to global scale mapping of the human settlement extent based on earth observation satellite data has made considerable progress. Nevertheless, the current approaches only provide a two-dimensional representation of the built environment ...
T. Esch +11 more
semanticscholar +1 more source
The TanDEM-X Mission Concept [PDF]
TanDEM-X opens a new era in space borne radar remote sensing. The first bistatic SAR mission, is formed by adding a second, almost identical spacecraft, to TerraSAR-X and flying the two satellites in a closely controlled formation with typical distances ...
Zink, Manfred +3 more
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

