Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
TanDEM-X Close Formation Flight AOCS Safety Measures and Operations [PDF]
The TanDEM-X project is implemented by a “Public-Private Partnership” between the German Aerospace Centre (DLR) and Astrium GmbH. The primary goal of the TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurement) mission is to generate a global ...
Schulze, Daniel +2 more
core
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Quality assessment of TanDEM-X Raw DEMs oriented to a fusion with CartoSAT-1 DEMs [PDF]
This paper addresses a quality assessment of TanDEM-X standard Raw DEMs, with a resolution of 12 meters, for three different terrain configurations: urban areas, moderate topography and complex topography.
Reinartz, Peter +4 more
core
Development of the TanDEM-X Calibration Concept: Analysis of Systematic Errors [PDF]
The TanDEM-X mission, result of the partnership between the German Aerospace Center (DLR) and Astrium GmbH, opens a new era in spaceborne radar remote sensing. The first bistatic satellite synthetic aperture radar mission is formed by flying the TanDEM-
Fiedler, Hauke +3 more
core +1 more source
On the Sensitivity of TanDEM-X-Observations to Boreal Forest Structure
The structure of forests is important to observe for understanding coupling to global dynamics of ecosystems, biodiversity, and management aspects. In this paper, the sensitivity of X-band to boreal forest stem volume and to vertical and horizontal ...
Jan I. H. Askne +2 more
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
The TanDEM-X DEM Mosaicking: Fusion of Multiple Acquisitions Using InSAR Quality Parameters
Since 2010, TanDEM-X and its twin satellite TerraSAR-X fly in a close orbit formation and form a single-pass synthetic aperture radar (SAR) interferometer.
Astrid Gruber +3 more
doaj +1 more source
Status of TanDEM-X DEM Calibration and Mosaicking towards the TanDEM-X DEM [PDF]
With begin of 2013 DEM production started with the generation of the Intermediate TanDEM-X DEM (IDEM) for selected science and commercial test sites. This paper gives an overview of the Intermediate DEM production that took place from end of 2012 until July 2013. It describes the DEM production process and the lessons learnt by the IDEM phase.
Wessel, Birgit +5 more
openaire +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source

