Results 101 to 110 of about 295,010 (304)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Towards Automatic SAR-Optical Stereogrammetry over Urban Areas using Very High Resolution Imagery

open access: yes, 2018
In this paper we discuss the potential and challenges regarding SAR-optical stereogrammetry for urban areas, using very-high-resolution (VHR) remote sensing imagery.
Qiu, Chunping   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Using TanDEM-X Pursuit Monostatic Observations with a Large Perpendicular Baseline to Extract Glacial Topography

open access: yesRemote Sensing, 2018
Space-based Interferometric Synthetic Aperture Radar (InSAR) applications have been widely used to monitor the cryosphere over past decades. Owing to temporal decorrelation, interferometric coherence often severely degrades on fast moving glaciers ...
Sang-Hoon Hong   +5 more
doaj   +1 more source

Potentials of TanDEM-X Interferometric Data for Global Forest/Non-Forest Classification [PDF]

open access: yes, 2016
This paper presents a method to generate forest/nonforest maps from TanDEM-X interferometric SAR data. Among the several contributions which may affect the quality of interferometric products, the coherence loss caused by volume scattering represents the
Bräutigam, Benjamin   +3 more
core  

Estimating site index from short term TanDEM-X canopy height models [PDF]

open access: yes, 2016
The tree height growth from three vegetation seasons was fitted to height growth curves in order to estimate the site index, which is a variable related to forest site productivity.
Fransson, Johan, Persson, Henrik
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Virtualizing Monitoring and Control Systems: First Operational Experience and Future Applications [PDF]

open access: yes, 2010
Virtualization is a technology that allows emulating a complete computer platform. The potential use ranges from consolidating hardware to running several different operating systems in parallel on one computer to preserving the operability of heritage ...
Kretschel, Ursula   +3 more
core  

Multistatic SAR Imaging: Comparison of Simulation Results and Experimental Data [PDF]

open access: yes, 2017
Synthetic aperture radar (SAR) systems in a multistatic configuration are a promising candidate for future Earth observation and reconnaissance radar systems. They overcome the sampling constraints inherent to single-channel SAR systems.
Bachmann, Markus   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy