Results 91 to 100 of about 295,010 (304)
Mapping Terrestrial Impact Craters with the TanDEM-X Digital Elevation Model [PDF]
The TanDEM-X mission generates a global digital elevation model (DEM) with unprecedented properties. We use it for mapping confirmed terrestrial impact craters as listed in the Earth Impact Database.
Breit, Helko +4 more
core
Non-Local Compressive Sensing Based SAR Tomography [PDF]
Tomographic SAR (TomoSAR) inversion of urban areas is an inherently sparse reconstruction problem and, hence, can be solved using compressive sensing (CS) algorithms.
Bamler, Richard +2 more
core +2 more sources
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
TanDEM-X Mission: Overview and Evaluation of intermediate Results [PDF]
The German Aerospace Center (DLR, Deutsches Zentrum für Luft- und Raumfahrt) currently conducts the bistatic interferometric synthetic aperture radar (SAR) Mission TanDEM-X, which shall result in a DEM of global coverage in an unprecedented resolution ...
U. Soergel, K. Jacobsen, L. Schack
doaj +1 more source
A fast and accurate basis pursuit denoising algorithm with application to super-resolving tomographic SAR [PDF]
$L_1$ regularization is used for finding sparse solutions to an underdetermined linear system. As sparse signals are widely expected in remote sensing, this type of regularization scheme and its extensions have been widely employed in many remote sensing
Bamler, Richard +3 more
core +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Two years of TanDEM-X baseline determination
The TanDEM-X mission is a German dual satellite formation with the task to acquire a global digital elevation model (DEM) by bistatic interferometric synthetic aperture radar (SAR) data takes. In order to reach the intended DEM accuracy, the two satellites are kept in formation with a distance of less than 500 m and the baseline vector between the two ...
Wermuth, M. +4 more
openaire +5 more sources
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

