Results 91 to 100 of about 684,338 (315)

Small molecule tandem organic photovoltaic cells incorporating an α-NPD optical spacer layer [PDF]

, 2013
We report an improvement in power conversion efficiency in a small molecule tandem organic photovoltaic (OPV) device by the optimisation of current balancing of the sub-cells using an optical spacer layer. A co-deposited layer of N,N’-bis(1-naphthyl)-N,N′
Howells, Thomas J., Jones, T. S. (Tim S.), Jones, Tim S., New, Edward G., Sullivan, Paul J., Howells, Thomas, New, Edward, Sullivan, Paul   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

TanDEM-X: A High Resolution Radar Topography Mission

, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer that is based on two high-resolution radar satellites in close formation flight: TerraSAR-X (launched on June 15, 2007) and TanDEM-X ...
Moreira, Alberto
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

TanDEM-X: A satellite formation for high-resolution SAR interferometry

, 2007
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was approved for full implementation by the German Space Agency in spring 2006. This paper gives an overview of the TanDEM-X
Hajnsek, Irena, H. Fiedler, A. Moreira, M. Zink, M. Bachmann, Fiedler, Hauke, Krieger, Gerhard, Hueso Gonzalez, Jaime, Werner, Marian, I. Hajnsek, Huber, Sigurd, Zink, Manfred, S. Huber, J.H. Gonzalez, Moreira, Alberto, Younis, Marwan, G. Krieger, Bachmann, Markus, M. Werner, M. Younis   +19 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Research on Flow-Induced Vibration and Energy Harvesting of Three Circular Cylinders with Roughness Strips in Tandem

Energies, 2018
The flow-induced vibration (FIV) of multiple cylinders is a common phenomenon in industry and nature. The FIV and energy harvesting of three circular cylinders in tandem are numerically studied by 2D-URANS simulations in Reynolds number range of 30,000 ...
Lin Ding, Qunfeng Zou, Li Zhang, Haibo Wang   +3 more
doaj   +1 more source

PERCENTILE OF TANDEM QUEUE

Journal of the Operations Research Society of Japan, 1985
Quite often, there are tandem queue systems the service facilities of which are serially linked; for example, computer systems that consist of two stages. In the general cases, the total time spent in the system corresponds to the response time. However, customers have a greater interest in upper deviation of the time than in the mean value as a ...
Ohmae, Yoshitsugu, Iwase, Eiyu
openaire   +3 more sources

TanDEM-X Scientific Results and Future Formation Flying SAR Missions

, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was launched on June 21, 2010. This paper gives an overview of scientific experiments that have been conducted during the TanDEM-
Lopez Dekker, Paco, De Zan, Francesco, Hajnsek, Irena, Rodriguez Cassola, Marc, Zink, Manfred, Moreira, Alberto, Prats, Pau, Baumgartner, Stefan, Papathanassiou, Konstantinos, Krieger, Gerhard   +9 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source