Results 101 to 110 of about 52,373 (299)

FLT3-ITD Incidence and FLT-D835 Mutations in Acute Myeloid Leukemia Patients with Normal Karyotype in Morocco: A Preliminary Study

Middle East Journal of Cancer, 2013
Background: According to numerous studies, FMS-like tyrosine kinase 3, internal tandem duplication, and the D835 mutation are associated with a poor prognostic clinical outcome in acute myeloid leukemia patients. Detection of the FMS-like tyrosine kinase
Hind Dehbi, Yaya Kassogue, Sanaa Nasserddine, Asma Quessar, Sellama Nadifi   +4 more
doaj  

Evolution of cytochrome P450 gene superfamily in different cellular organisms

Frontiers in Ecology and Evolution
Cytochrome P450 enzymes, a widespread monooxygenase superfamily, are crucial for metabolic diversity and environmental adaptation. However, systematic analysis and comparison of the expansion of the P450 gene superfamily and its potential mechanisms in ...
Yuxia Shi, Yuxia Shi, Shu Zong, Shu Zong, Hejian Zhang, Hejian Zhang, Shuo Liu, Shuo Liu, Junru Yang, Lina Lu, Xiaonan Liu, Xiaonan Liu, Jian Cheng, Huifeng Jiang   +13 more
doaj   +1 more source

Gene Duplication Analysis Reveals No Ancient Whole Genome Duplication but Extensive Small-Scale Duplications during Genome Evolution and Adaptation of Schistosoma mansoni

Frontiers in Cellular and Infection Microbiology, 2017
Gene duplication (GD), thought to facilitate evolutionary innovation and adaptation, has been studied in many phylogenetic lineages. However, it remains poorly investigated in trematodes, a medically important parasite group that has been evolutionarily ...
Shuai Wang, Xing-quan Zhu, Xuepeng Cai
doaj   +1 more source

Molecularly defined interstitial tandem duplication 6p case with mild manifestations.

, 2001
An interstitial tandem duplication of 6p21.1-p22.2 was found in a girl at 11 months of age when she was evaluated for developmental delay. Previous cases reported with partial 6p duplication usually have involved terminal duplications, with breakpoints ...
Mirza, G, Mowrey, P, Turner, C, Di Fazio, MP, Ragoussis, J, Coll, E, Di Fazio, Di, Levin, SW, Ng, D   +8 more
core   +1 more source

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

Advanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang, Yiting Wang, Yuxin You, Zhiyue Wu, Dongbao Li, Xin Wang, Yongsheng Chang, Hang Zhao, Tao Zhu, Dijun Chen, Wei Chen, Bo Sun   +11 more
wiley   +1 more source

Tandem Duplication [PDF]

Journal of Biological Chemistry, 2000
Anna Pluciennik, Ravi R. Iyer, Pawel Parniewski, Robert D. Wells   +3 more
openaire   +1 more source

Sorting signed permutations by tandem duplication random loss and inverse tandem duplication random loss

Advances in Applied Mathematics
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bruno J. Schmidt, Tom Hartmann, Peter F. Stadler   +2 more
openaire   +1 more source

Characterization of intragenic tandem duplication in the PAFAH1B1 gene leading to isolated lissencephaly sequence.

, 2015
the Creative Commons Attribution 4.0BACKGROUND: Genetic aberrations in PAFAH1B1 result in isolated lissencephaly sequence (ILS), a neuronal migration disorder associated with severe mental retardation and intractable epilepsy.
高橋, 悟, Takahashi, Satoru, Okano, Satomi, タカハシ, サトル, Azuma, Hiroshi, 田中, 亮介, オカヤマ, アキエ, スズキ, ナオ, Suzuki, Nao, 岡野, 聡美, 岡山, 亜貴恵, 東, 寛, Okayama, Akie, アズマ, ヒロシ, オカノ, サトミ, Tanaka, Ryosuke, タナカ, リョウスケ, 鈴木, 菜生   +17 more
core   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

The clinical and biological consequences of different FLT3 mutations in patients with AML

, 2009
Characterisation of pathogenic markers in acute myeloid leukaemia (AML) may benefit patients through refinement of risk stratification, application of molecularly targeted therapy and improved understanding of AML biology.
Mead, A.J.
core