Results 101 to 110 of about 887,704 (273)

Stroke Lesion Prediction by Bille-Viper-Segmentation with Tandem-MU-net Model [PDF]

Advanced Ultrasound in Diagnosis and Therapy
Stroke is a critical condition marked by the death of brain cells due to inadequate blood flow, necessitating improved predictive models for stroke lesions.
Beevi Fathima, N Santhi Dr, N Ramasamy Dr
doaj   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

Cartilage Delamination Flap Mimicking a Torn Medial Meniscus

Case Reports in Orthopedics, 2016
We report a case of a chondral delamination lesion due to medial parapatellar plica friction syndrome involving the medial femoral condyle. This mimicked a torn medial meniscus in clinical and radiological presentation.
Gan Zhi-Wei Jonathan, Hamid Rahmatullah Bin Abd Razak, Mitra Amit Kanta   +2 more
doaj   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

TanDEM-X: A satellite formation for high-resolution SAR interferometry [PDF]

, 2007
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was approved for full implementation by the German Space Agency in spring 2006. This paper gives an overview of the TanDEM-X
Hajnsek, Irena, H. Fiedler, A. Moreira, M. Zink, M. Bachmann, Fiedler, Hauke, Krieger, Gerhard, Hueso Gonzalez, Jaime, Werner, Marian, I. Hajnsek, Huber, Sigurd, Zink, Manfred, S. Huber, J.H. Gonzalez, Moreira, Alberto, Younis, Marwan, G. Krieger, Bachmann, Markus, M. Werner, M. Younis   +19 more
core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Hemodynamic Tandem Intracranial Lesions on Magnetic Resonance Angiography in Patients Undergoing Carotid Endarterectomy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundHemodynamic tandem intracranial lesions (TILs) on intracranial magnetic resonance angiography, which develop flow dependently, have been overlooked clinically in patients undergoing carotid endarterectomy.
Eun‐Jae Lee, Yong‐Pil Cho, Sang‐Hun Lee, Ji Sung Lee, Hyo Jung Nam, Bum Joon Kim, Tae‐Won Kwon, Dong‐Wha Kang, Jong S. Kim, Sun U. Kwon   +9 more
doaj   +1 more source

Bistatic SAR Experiments with the TanDEM-X Constallation [PDF]

, 2012
Launched in June 2010, TanDEM-X is an interferometric mission with the main goal of providing a high-resolution, global and unprecedentedly accurate digital elevation model (DEM) of the Earth by means of single-pass X-band SAR interferometry. Despite
Steinbrecher, Ulrich, Nottensteiner, Anton, Martin Keller, Marc Rodriguez-Cassola, Horn, Ralf, Pau Prats, Ralf Horn, Rodriguez-Cassola, Marc, Pinheiro, Muriel, Krieger, Gerhard, Daniel Schulze, Keller, Martin, Muriel Pinheiro, Schulze, Daniel, Ulrich Steinbrecher, Manfred Zink, Anton Nottensteiner, Alberto Moreira, Zink, Manfred, Andreas Reigber, Moreira, Alberto, Prats, Pau, Reigber, Andreas, Gerhard Krieger   +23 more
core   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source

The TanDEM-X Mission: Overview and Status [PDF]

, 2007
TanDEM-X opens a new era in space borne radar remote sensing. The first bistatic SAR mission, is formed by adding a second, almost identical spacecraft, to TerraSARX and flying the two satellites in a closely controlled formation with typical ...
Werner, Marian, Hajnsek, Irena, Zink, Manfred, Moreira, Alberto, Fiedler, Hauke, Krieger, Gerhard   +5 more
core   +2 more sources