Results 81 to 90 of about 832,301 (284)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Safety and Efficacy of Low-Dose Eptifibatide for Tandem Occlusions in Acute Ischemic Stroke

open access: yesNeurology International
Objectives: The optimal treatment strategy for ischemic stroke in patients presenting with tandem occlusions of the internal carotid artery remains controversial.
Paweł Latacz   +5 more
doaj   +1 more source

TanDEM-X Commissioning Phase Status [PDF]

open access: yes, 2010
TanDEM-X is an Earth Observation mission, result of the cooperation of the German Aerospace Center (DLR) and EADS Astrium GmbH, consisting of two twin synthetic aperture radar (SAR) satellites, TerraSAR-X (TSX) and TanDEM-X (TDX).
Jaime Hueso Gonzalez   +5 more
core   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Tandem repeat copy-number variation in protein-coding regions of human genes [PDF]

open access: yes, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T.   +7 more
core   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

Radiation-induced formation of purine lesions in single and double stranded DNA: Revised quantification

open access: yesFrontiers in Chemistry, 2015
The formation of oxidative lesions arising from double stranded DNA damage is of major significance to chemical biology from the perspective of application to human health.
Michael A. Terzidis   +3 more
doaj   +1 more source

Flight Dynamics Operations of the TanDEM-X Formation [PDF]

open access: yes, 2012
Since end of 2010 the German TerraSAR-X and TanDEM-X satellites are routinely operated as the first configurable single-pass Synthetic Aperture Radar interferometer in space. The two 1340 kg satellites fly in a 514 km sun-synchronous orbit.
Aida, Saika   +4 more
core   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

open access: yesAdvanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi   +13 more
wiley   +1 more source

Non-nominal Experimental Bistatic SAR Acquisitions with TanDEM-X [PDF]

open access: yes, 2012
TanDEM-X is a high-resolution interferometric mission with the main goal of providing a global and unprecedentedly accurate digital elevation model (DEM) of the Earth surface by means of single-pass X-band SAR interferometry.
Schulze, Daniel   +10 more
core  

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