Results 61 to 70 of about 887,704 (273)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Stroke: Vascular and Interventional Neurology, 2022 Background Patients with acute ischemic stroke due to large vessel occlusion may present with concomitant carotid dissections that make the technical approach for their treatment challenging.
Humberto Diaz‐Silva +17 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Malignant Solitary Fibrous Tumor of Tandem Lesions in the Skull and Spine
Journal of Korean Neurosurgical Society, 2013 A Solitary Fibrous Tumor (Sft) Is A Rare Neoplasm Originated From The Pleura, But They Can Occur In A Variety Of Extrathoracic Regions. Although Many Cases Of Primary Sft Have Been Reported, There Are Extremely Rare Repots To Date Of A Malignant Sft In The Spine Or Skull.
Son, Seong +3 more
openaire +2 more sources
Quality assessment of TanDEM-X Raw DEMs oriented to a fusion with CartoSAT-1 DEMs [PDF]
, 2013 This paper addresses a quality assessment of TanDEM-X standard Raw DEMs, with a resolution of 12 meters, for three different terrain configurations: urban areas, moderate topography and complex topography.
Reinartz, Peter +4 more
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
TanDEM-X Scientific Results and Future Formation Flying SAR Missions [PDF]
, 2011 TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was launched on June 21, 2010. This paper gives an overview of scientific experiments that have been conducted during the TanDEM-
Lopez Dekker, Paco +9 more
core
The TanDEM-X Mission: Overview and Status [PDF]
, 2009 TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that will be launched in autumn 2009. This paper gives an overview of the TanDEM-X mission concept, summarizes the basic products,
Hajnsek, Irena +23 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Validation of functional state of coronary tandem lesions using computational flow dynamics
, 2012 Functional lesion assessment for coronary tandem lesions and its clinical applications have not been thoroughly studied. The aim of this study was to test the hypothesis that the fractional flow reserve (FFR) gradient across an individual stenosis (ΔFFR)
Kim, Young Tae +14 more
core +1 more source