Results 71 to 80 of about 832,301 (284)

Mutagenesis and Repair of γ-Radiation- and Radical-Induced Tandem DNA Lesions

open access: yesDNA
Ionizing radiation induces many different types of DNA lesions. But one of its characteristics is to produce complex DNA damage, of which tandem DNA damage has received much attention, owing to its promise of distinctive biological properties.
Ashis K. Basu   +2 more
doaj   +1 more source

Successful treatment of tandem calcific right coronary artery stenoses with 50 mm tapered Biomime Morph stent guided by intravascular ultrasound and rotablation using a sheathless guide via the radial access

open access: yesIHJ Cardiovascular Case Reports, 2019
Tandem and/or diffuse calcific coronary stenoses can present significant challenges during percutaneous coronary intervention (PCI). Often, these long lesions require treatment with multiple stents of different calibers. However, this approach can result
Baskar Sekar   +2 more
doaj   +1 more source

TanDEM-X Scientific Results and Future Formation Flying SAR Missions [PDF]

open access: yes, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative spaceborne radar interferometer mission that was launched on June 21, 2010. This paper gives an overview of scientific experiments that have been conducted during the TanDEM-
Lopez Dekker, Paco   +9 more
core  

Bistatic SAR Experiments with the TanDEM-X Constallation [PDF]

open access: yes, 2012
Launched in June 2010, TanDEM-X is an interferometric mission with the main goal of providing a high-resolution, global and unprecedentedly accurate digital elevation model (DEM) of the Earth by means of single-pass X-band SAR interferometry. Despite
Steinbrecher, Ulrich   +23 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The TanDEM-X Acquisition Timeline and Mission Plan [PDF]

open access: yes, 2008
This paper introduces the TanDEM-X data acquisition plan that fulfils the requirements of deriving a global DEM according to the emerging HRTI-3 quality standard within three years mission time. Therefore, a joint TerraSAR-X and TanDEM-X data acquisition
Zink, Manfred   +4 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

The Influence of Single, Tandem, and Clustered DNA Damage on the Electronic Properties of the Double Helix: A Theoretical Study

open access: yesMolecules, 2020
Oxidatively generated damage to DNA frequently appears in the human genome as the effect of aerobic metabolism or as the result of exposure to exogenous oxidizing agents, such as ionization radiation.
Bolesław T. Karwowski
doaj   +1 more source

The TanDEM-X Mission Concept [PDF]

open access: yes, 2008
TanDEM-X opens a new era in space borne radar remote sensing. The first bistatic SAR mission, is formed by adding a second, almost identical spacecraft, to TerraSAR-X and flying the two satellites in a closely controlled formation with typical distances ...
Zink, Manfred   +3 more
core  

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