Results 51 to 60 of about 887,704 (273)
DNA Damage by Ionizing Radiation: Tandem Double Lesions by Charged Particles [PDF]
, 2005 Oxidative damages by ionizing radiation are the source of radiation-induced carcinogenesis, damage to the central nervous system, lowering of the immune response, as well as other radiation-induced damages to human health.
Dateo, Christopher E. +3 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
TanDEM-X Experiments in Pursuit Monostatic Configuration [PDF]
, 2012 This paper reports on several experiments performed by the TanDEM-X constellation that could be potentially implemented as operational modes in future SAR missions.
Steinbrecher, Ulrich +12 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Frontiers in Neurology, 2019 Introduction: Endovascular therapy has been shown to be an effective and safe treatment for tandem occlusion. The endovascular therapeutic strategies for tandem occlusions strokes have not been adequately evaluated and the best approach is still ...
François Zhu +16 more
doaj +1 more source
TanDEM-X Mission and DEM Accuracy [PDF]
, 2009 TanDEM-X (TerraSAR-X Add-on for Digital Elevation Measurements) is currently implemented as a national Earth observation mission by the German Aerospace (DLR) and EADS Astrium GmbH.
Johannes, Böer +5 more
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Wake-induced transverse vibration of two interfering cylinders in tandem arrangement : modelling and analysis [PDF]
, 2013 This paper discusses wake-induced transverse vibration of two interfering cylinders in tandem ...
Armin, Milad, Srinil, Narakorn
core +4 more sources
Вестник хирургии имени И.И. Грекова, 2021 RELEVANCE. Pathological tortuosity of the carotid artery and thrombotic occlusion of the intracranial segment of the carotid artery, critical subostial stenosis are the main causes of tandem lesions in patients with intracranial cerebral artery occlusion.
I P. Dudanov +5 more
doaj +1 more source