Results 51 to 60 of about 832,301 (284)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurement) opens a new era in spaceborne radar remote sensing [1]. A single-pass SAR interferometer with adjustable baselines in across- and in along-track directions is formed by adding a second (TDX),
Schulze, Daniel +4 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Introduction: Endovascular therapy has been shown to be an effective and safe treatment for tandem occlusion. The endovascular therapeutic strategies for tandem occlusions strokes have not been adequately evaluated and the best approach is still ...
François Zhu +16 more
doaj +1 more source
TanDEM-X Mission and DEM Accuracy [PDF]
TanDEM-X (TerraSAR-X Add-on for Digital Elevation Measurements) is currently implemented as a national Earth observation mission by the German Aerospace (DLR) and EADS Astrium GmbH.
Johannes, Böer +5 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
RELEVANCE. Pathological tortuosity of the carotid artery and thrombotic occlusion of the intracranial segment of the carotid artery, critical subostial stenosis are the main causes of tandem lesions in patients with intracranial cerebral artery occlusion.
I P. Dudanov +5 more
doaj +1 more source
TANDEM-X: A RADAR INTERFEROMETER WITH TWO FORMATION FLYING SATELLITES [PDF]
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurements) is an innovative formation flying radar mission that opens a new era in spaceborne radar remote sensing.
Zink, Manfred +2 more
core
Interferometric Sea Ice Mapping with TanDEM-X: First Experiments [PDF]
In summer 2010 during the commissioning phase of TanDEM-X, the TerraSAR-X/TanDEM-X constellation was operated in the pursuit monostatic mode allowing alongtrack interferometric measurements with very short time separation of only 2.6 sec.
Sant’Anna Araújo, Laís +11 more
core +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

