Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. [PDF]
, 2012 Recruitment of 53BP1 to chromatin flanking double strand breaks (DSBs) requires γH2AX/MDC1/RNF8-dependent ubiquitination of chromatin and interaction of 53BP1 with histone H4 methylated on lysine 20 (H4K20me). Several histone methyltransferases have been
Guan, Yinghua +7 more
core +8 more sources
Computational and Structural Biotechnology Journal, 2021 The combination of several closely spaced DNA lesions, which can be induced by a single radical hit, constitutes a hallmark in the DNA damage landscape and radiation chemistry.
Emmanuelle Bignon +5 more
doaj +1 more source
Molecular epidemiology of Mycobacterium bovis in Cameroon [PDF]
, 2017 We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201
Asuquo, A. +13 more
core +2 more sources
Utility of mass spectrometry for the diagnosis of the unstable coronary plaque. [PDF]
, 2015 Mass spectrometry is a powerful technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structure and chemical properties of molecules.
Hassan, M, Jacob, SS, Yacoub, MH
core +1 more source
Stroke: Vascular and Interventional Neurology, 2023 Introduction Simultaneous extracranial‐intracranial management of Tandem lesion in stroke (Seimless technique) is well published and important technique in treating tandem lesions in anterior circulation.
Samer AbdulVarun Kareemchaubal +3 more
doaj +1 more source
Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]
, 2017 BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine +5 more
core +1 more source
Emergent Carotid Stenting After Thrombectomy in Patients With Tandem Lesions [PDF]
Stroke, 2017 A 68-year-old diabetic woman presents to the emergency department 1 hour after right-sided hemiplegia and global aphasia. National Institutes of Health Stroke Scale score is 21; Alberta Stroke Program Early CT score (ASEPCTS) on computed tomographic scan is 8; and computed tomographic angiography shows severe left internal carotid artery stenosis and ...
Behme, Daniel +3 more
openaire +3 more sources
Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]
, 2006 It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko +3 more
core +1 more source
Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis. [PDF]
, 2020 Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC ...
Cho, Byong Seung +19 more
core +1 more source
Emergent Management of Tandem Lesions in Acute Ischemic Stroke. [PDF]
Stroke, 2019 Background and Purpose- Although intracranial thrombectomy represents the standard treatment approach for anterior circulation tandem occlusions, whether the extracranial lesion requires acute stenting remains unclear. Our aim was to investigate differences in clinical and procedural outcomes related to stenting extracranial lesions in a registry of ...
Ashutosh P, Jadhav +10 more
openaire +3 more sources