Results 11 to 20 of about 832,301 (284)

Fragile sites, chromosomal lesions, tandem repeats, and disease

open access: yesFrontiers in Genetics, 2022
Expanded tandem repeat DNAs are associated with various unusual chromosomal lesions, despiralizations, multi-branched inter-chromosomal associations, and fragile sites.
Mila Mirceta   +7 more
doaj   +3 more sources

Effect of tandem lesions on hemodynamic parameters: an experimental study [PDF]

open access: yesKardiologia Polska, 2017
WOS: 000424153600005PubMed ID: 28832097Background and aim: The morphology and extensity of the stenotic lesion is crucial as well as the obstruction ratio.
Hanedan, Onur   +11 more
core   +5 more sources

The T-Top Technique for Tandem Lesions: A Single-Center Retrospective Study [PDF]

open access: yesJournal of Clinical Medicine
Background: Tandem Lesions (TLs) or Tandem Occlusions (TOs) are characterized by simultaneous high-grade stenosis or occlusion of the proximal extracranial internal carotid artery and the intracranial terminal internal carotid artery or its branches. These lesions can result in stroke and pose significant challenges to endovascular treatment.
Matteo de Simone, Renato Saponiero
exaly   +5 more sources

Effect of the Cervical Lesion Severity on Procedural and Clinical Outcomes after Endovascular Treatment of Acute Tandem Lesions: A Multicenter Study [PDF]

open access: yesStroke: Vascular and Interventional Neurology
Background Tandem lesions pose unique challenges in the endovascular treatment of acute ischemic stroke. We aimed to compare the clinical and procedural outcomes of patients with tandem lesions and extracranial internal carotid artery (ICA) complete ...
Milagros Galecio‐Castillo   +34 more
doaj   +2 more sources

Endovascular Treatment of Patients With Acute Ischemic Stroke With Tandem Lesions Presenting With Low Alberta Stroke Program Early Computed Tomography Score [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Recent trials confirmed the efficacy and safety of endovascular thrombectomy in patients with low Alberta Stroke Program Early Computed Tomography Score (ASPECTS); however, evidence in tandem lesions is limited.
Milagros Galecio‐Castillo   +36 more
doaj   +2 more sources

Relevance of Carotid Reocclusion in Tandem Lesions. [PDF]

open access: yesJ Atheroscler Thromb, 2023
Carotid reocclusion (CRO) after mechanical thrombectomy (MT) in acute ischemic stroke (AIS) due to tandem lesion (TL) or isolated internal carotid occlusion (ICO) is associated with worse clinical outcomes. Our aim was to analyze the predictors and clinical impact of CRO.A retrospective single-center analysis of all patients with anterior circulation ...
Zapata-Arriaza E   +13 more
europepmc   +4 more sources

Endovascular treatment of a tandem lesion in the anterior circulation: results of the tandem MN study

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Endovascular management of acute stroke caused by a tandem lesion in the anterior circulation is currently a discussed area. Acute insertion of a carotid stent in the absence of antiaggregation premedication often leads to acute stent ...
David Cernik   +5 more
doaj   +2 more sources

The Influence of 5′R and 5′S cdA and cdG on the Activity of BsmAI and SspI Restriction Enzymes

open access: yesMolecules, 2021
Restriction endonucleases (REs) are intra-bacterial scissors that are considered tools in the fight against foreign genetic material. SspI and BsmAI, examined in this study, cleave dsDNA at their site of recognition or within a short distance of it. Both
Michał Szewczuk   +3 more
doaj   +1 more source

When UDG and hAPE1 Meet Cyclopurines. How (5′R) and (5′S) 5′,8-Cyclo-2′-deoxyadenosine and 5′,8-Cyclo-2′-deoxyguanosine Affect UDG and hAPE1 Activity?

open access: yesMolecules, 2021
Ionizing radiation is a factor that seriously damages cellular mechanisms/macromolecules, e.g., by inducing damage in the human genome, such as 5′,8-cyclo-2′-deoxypurines (cdPus).
Michał Szewczuk   +3 more
doaj   +1 more source

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