Advances in the Detection of Immunosuppressive Agents in Blood by Mass Spectrometry
Zhipu XuebaoImmunosuppressive drugs are mainly used to fight against immune rejection after organ transplantation, and have great potential to reduce the incidence rate and mortality of patients.
Fei PAN +8 more
doaj +1 more source
ANALYTICAL FEATURES OF SYNTHETIC MDMB(N)-073F CANNABIMIMETICS AND ITS MARKERS IN BIOLOGICAL MATERIAL
Фармация и фармакология (Пятигорск), 2019 The aim of the research is to study both analytical features of synthetic MDMB(N)-073F cannabimimetics of indazole carboxamides group by gas chromatography methods combined with tandem mass spectrometry (GC-MS) and high performance liquid chromatography ...
S. S. Kataev +4 more
doaj +1 more source
Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]
, 2013 The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David +7 more
core +2 more sources
Newborn Sickle Cell Disease Screening Using Electrospray Tandem Mass Spectrometry
International Journal of Neonatal Screening, 2018 There is a growing demand for newborn sickle cell disease screening globally. Historically techniques have relied on the separation of intact haemoglobin tetramers using electrophoretic or liquid chromatography techniques.
Yvonne Daniel, Charles Turner
doaj +1 more source
Machine learning meets mass spectrometry: a focused perspective [PDF]
arXivMass spectrometry is a widely used method to study molecules and processes in medicine, life sciences, chemistry, catalysis, and industrial product quality control, among many other applications. One of the main features of some mass spectrometry techniques is the extensive level of characterization (especially when coupled with chromatography and ion ...
arxiv
Mining Mass Spectra: Metric Embeddings and Fast Near Neighbor Search [PDF]
arXiv, 2006 Mining large-scale high-throughput tandem mass spectrometry data sets is a very important problem in mass spectrometry based protein identification. One of the fundamental problems in large scale mining of spectra is to design appropriate metrics and algorithms to avoid all-pair-wise comparisons of spectra. In this paper, we present a general framework
arxiv
Application of computational quantum chemistry to chemical processes involved in mass spectrometry [PDF]
, 2008 The field of application of mass spectrometry (MS) has increased considerably due to the development of ionization techniques. Other factors that have stimulated the use of MS are the tandem mass spectrometry (MS/MS) and sequential mass spectrometry (MSn)
CROTTI, Antônio E. M. +4 more
core +2 more sources
Monolysocardiolipin in cultured fibroblasts is a sensitive and specific marker for Barth Syndrome
Journal of Lipid Research, 2006 Barth Syndrome (BTHS) is an X-linked recessive disorder that results in abnormal metabolism of the mitochondrial phospholipid cardiolipin (CL). CLs are decreased and monolysocardiolipins (MLCLs), intermediates in CL metabolism, are increased in a variety
Michiel Adriaan van Werkhoven +3 more
doaj
Towards Less Biased Data-driven Scoring with Deep Learning-Based End-to-end Database Search in Tandem Mass Spectrometry [PDF]
arXivPeptide identification in mass spectrometry-based proteomics is crucial for understanding protein function and dynamics. Traditional database search methods, though widely used, rely on heuristic scoring functions and statistical estimations have to be introduced for a higher identification rate.
arxiv
Top-Down Mass Spectrometry Imaging of Intact Proteins by LAESI FT-ICR MS [PDF]
arXiv, 2013 Laser Ablation Electrospray Ionization is a recent development in mass spectrometry imaging. It has been shown that lipids and small metabolites can be imaged in various samples such as plant material, tissue sections or bacterial colonies without anysample pre-treatment.
arxiv