Results 181 to 190 of about 988,611 (339)

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

SimMS: a GPU-accelerated cosine similarity implementation for tandem mass spectrometry. [PDF]

Bioinformatics
Onoprishvili T, Yuan JH, Petrov K, Ingalalli V, Khederlarian L, Leuchtenmuller N, Chandra S, Duarte A, Bender A, Gloaguen Y.   +9 more
europepmc   +1 more source

Electrospray tandem mass spectrometry of aminochromes [PDF]

, 2001
Francisco Amado, Pedro Domíngues, A. J. Ferrer‐Correia, Fernando Remião, Nuno Milhazes, Fernanda Borges, Félix Carvalho, Maria de Lourdes Bastos   +7 more
openalex   +1 more source

SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling

Advanced Science, EarlyView.
As a downstream target of α2δ1‐mediated calcium signaling, SIRT4 serves as an oncogene to promote the stemness of pancreatic cancer via deacetylating ENO1 directly at K358, leading to attenuated ENO1's RNA‐binding capacity, enhanced glycolytic substrate 2‐PG binding and robust glycolytic activity to increase the level of lactate that induce histone ...
Mengzhu Lv, Xiaodan Yang, Congcong Xu, Qingru Song, Hailian Zhao, Tianjiao Sun, Jingtao Liu, Yuan Zhang, Guogui Sun, Yuanchao Xue, Zhiqian Zhang   +10 more
wiley   +1 more source

Correlations of Free Thyroid Hormones Measured by Tandem Mass Spectrometry and Immunoassay in Dogs. [PDF]

Animals (Basel)
Sasso R, Siniscalchi M, d'Ingeo S, Ventriglia G, Bitetto C, Quaranta A.   +5 more
europepmc   +1 more source

Tandem Mass Spectrometry

Mass Spectrometry, 2019
P. Suder
semanticscholar   +1 more source

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

Advanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu, Xing Zhao, Ting Jiang, Ningjuan Ouyang, Peilin Li, Wei Yang, Zhihe Zhao   +6 more
wiley   +1 more source

Tandem Mass Spectrometry for Peptide and Protein Sequence Analysis

BioTechniques, 2005
Joshua J. Coon, John E.P. Syka, Jeffrey Shabanowitz, Donald F. Hunt   +3 more
doaj   +1 more source

Tandem mass spectrometry in screening for inborn errors of metabolism: comprehensive bibliometric analysis. [PDF]

Front Pediatr
Kononets V, Zharmakhanova G, Balmagambetova S, Syrlybayeva L, Berdesheva G, Zhussupova Z, Tautanova A, Kurmambayev Y.   +7 more
europepmc   +1 more source

Determination of purine compounds in carotid artery plaque by liquid chromatography electrospray ionization tandem mass spectrometry [PDF]

, 2001
Silvia Catinella, Nicola Pelizzi, Renzo Marsilio, Margherita Zanol, Brunetta Porcelli, Lucia Terzuoli, M Giubbolini, Carlo Setacci   +7 more
openalex   +1 more source