Results 301 to 310 of about 988,611 (339)

Application of tandem mass spectrometry in the screening and diagnosis of mucopolysaccharidoses. [PDF]

Orphanet J Rare Dis
Li JW, Mao SJ, Chao YQ, Hu CX, Qian YJ, Dai YL, Huang K, Shen Z, Zou CC.   +8 more
europepmc   +1 more source

Stability Evaluation and Pharmacokinetic Profiling of Vepdegestrant in Rodents Using Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Molecules
Choi HI, Choi J, Kim JW, Lee YH, Cho KH, Koo TS.   +5 more
europepmc   +1 more source

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A statistical model for identifying proteins by tandem mass spectrometry.

Analytical Chemistry, 2003
A statistical model is presented for computing probabilities that proteins are present in a sample on the basis of peptides assigned to tandem mass (MS/MS) spectra acquired from a proteolytic digest of the sample.
A. Nesvizhskii, Andrew Keller, E. Kolker, R. Aebersold   +3 more
semanticscholar   +1 more source

Characterization of nucleic acids by tandem mass spectrometry - The second decade (2004-2013): From DNA to RNA and modified sequences.

Mass spectrometry reviews (Print), 2016
Nucleic acids play key roles in the storage and processing of genetic information, as well as in the regulation of cellular processes. Consequently, they represent attractive targets for drugs against gene-related diseases.
S. Schürch
semanticscholar   +1 more source

Overcoming spectral overlap via inductively coupled plasma-tandem mass spectrometry (ICP-MS/MS). A tutorial review

, 2017
This work reviews the operating principles of ICP-tandem mass spectrometry (ICP-MS/MS) and the key applications reported on since the introduction of the technique in 2012.
E. Bolea-Fernandez, L. Balcaen, M. Resano, F. Vanhaecke   +3 more
semanticscholar   +1 more source

Negative ion electrospray high-resolution tandem mass spectrometry of polyphenols.

Journal of Mass Spectrometry, 2016
Representative compounds with a 1,3-dihydroxybenzene substructure belonging to different important polyphenol classes (stilbenes, flavones, isoflavones, flavonols, flavanones, flavanols, phloroglucinols, anthraquinones and bisanthraquinones) were ...
Jürgen Schmidt
semanticscholar   +1 more source

PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry.

Rapid Communications in Mass Spectrometry, 2003
A number of different approaches have been described to identify proteins from tandem mass spectrometry (MS/MS) data. The most common approaches rely on the available databases to match experimental MS/MS data. These methods suffer from several drawbacks
Bin Ma, Kaizhong Zhang, Christopher Hendrie, Chengzhi Liang, Ming Li, A. Doherty-Kirby, Gilles Lajoie   +6 more
semanticscholar   +1 more source

Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome.

Journal of Proteome Research, 2003
Highly complex protein mixtures can be directly analyzed after proteolysis by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In this paper, we have utilized the combination of strong cation exchange (SCX) and reversed-phase (RP ...
Junmin Peng, Joshua E. Elias, Carson C. Thoreen, L. Licklider, S. Gygi   +4 more
semanticscholar   +1 more source

Probability‐based protein identification by searching sequence databases using mass spectrometry data

Electrophoresis, 1999
Several algorithms have been described in the literature for protein identification by searching a sequence database using mass spectrometry data. In some approaches, the experimental data are peptide molecular weights from the digestion of a protein by ...
D. N. Perkins, D. Pappin, D. Creasy, J. Cottrell   +3 more
semanticscholar   +1 more source

Radical-driven peptide backbone dissociation tandem mass spectrometry.

Mass spectrometry reviews (Print), 2015
In recent years, a number of novel tandem mass spectrometry approaches utilizing radical-driven peptide gas-phase fragmentation chemistry have been developed.
H. Oh, Bongjin Moon
semanticscholar   +1 more source