Results 341 to 350 of about 955,547 (405)

Characterization of nucleic acids by tandem mass spectrometry - The second decade (2004-2013): From DNA to RNA and modified sequences.

Mass spectrometry reviews (Print), 2016
Nucleic acids play key roles in the storage and processing of genetic information, as well as in the regulation of cellular processes. Consequently, they represent attractive targets for drugs against gene-related diseases.
S. Schürch
semanticscholar   +1 more source

Negative ion electrospray high-resolution tandem mass spectrometry of polyphenols.

Journal of Mass Spectrometry, 2016
Representative compounds with a 1,3-dihydroxybenzene substructure belonging to different important polyphenol classes (stilbenes, flavones, isoflavones, flavonols, flavanones, flavanols, phloroglucinols, anthraquinones and bisanthraquinones) were ...
Jürgen Schmidt
semanticscholar   +1 more source

Tandem Mass Spectrometry

Science, 1981
Coupling mass spectrometers in series provides a new technique that has many advantages for the analysis of specific organic compounds in complex mixtures. Sensitivity to picograms of targeted compounds can be achieved with high specificity and nearly instantaneous response.
openaire   +2 more sources

Tandem mass spectrometry of amidated peptides

Journal of Mass Spectrometry, 2006
AbstractThe behavior of C‐terminal amidated and carboxylated peptides upon low‐energy collision‐induced dissociation (CID) was investigated. Two sets of 76 sequences of variable amino acid compositions and lengths were synthesized as model compounds.
Mouls, Laetitia, Subra, Gilles, Aubagnac, Jean-Louis, Enjalbal, Christine, Martinez, Jean   +4 more
openaire   +4 more sources

Tandem mass spectrometry of synthetic polymers

Journal of Mass Spectrometry, 2009
AbstractThe detailed characterization of macromolecules plays an important role for synthetic chemists to define and specify the structure and properties of the successfully synthesized polymers. The search for new characterization techniques for polymers is essential for the continuation of the development of improved synthesis methods.
Anja Baumgaertel, Ulrich S. Schubert, Ulrich S. Schubert, Anna C. Crecelius   +3 more
openaire   +3 more sources

Peptide quantification by tandem mass spectrometry

Mass Spectrometry Reviews, 1996
This manuscript reviews the literature on the mass spectrometry (MS) and tandem mass spectrometry (MS/MS) quantification of biologically important peptides that have been extracted from tissues. The most important aspect of this quantification process is the use of MS/MS to link the protonated molecule ion, (M + H)(+) , of the peptide with one or more ...
Dominic M. Desiderio, Xuegong Zhu
openaire   +3 more sources

Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome.

Journal of Proteome Research, 2003
Highly complex protein mixtures can be directly analyzed after proteolysis by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In this paper, we have utilized the combination of strong cation exchange (SCX) and reversed-phase (RP ...
Junmin Peng, Joshua E. Elias, Carson C. Thoreen, L. Licklider, S. Gygi   +4 more
semanticscholar   +1 more source

Tandem Ionization Mass Spectrometry of Biomolecules

European Journal of Mass Spectrometry, 2000
The novel mass spectrometric technique tandem ionization mass spectrometry (TIMS) employs irradiation of gas-phase even-electron molecular ions of both polarities with >10 eV electrons. This leads to the production of radical molecular cations and anions of large biomolecules.
Zubarev, R.A., Budnik, B.A., Nielsen, M.L.   +2 more
openaire   +3 more sources

[40] Tandem mass spectrometry of glycolipids

1990
Publisher Summary This chapter describes a systematic nomenclature for fragments observed in the mass spectra of glycolipids, the use of a high-performance tandem mass spectrometer (high mass range, with unit resolution or better available in both MS-1 and MS-2), and targeted derivatization procedures for glycolipid structural determinations ...
Catherine E. Costello, James E. Vath
openaire   +3 more sources

Electrospray tandem mass spectrometry of lexitropsins

Rapid Communications in Mass Spectrometry, 2001
AbstractSeveral compounds, representative of the class of lexitropsins, were analyzed by electrospray tandem mass spectrometry. The study of the fragmentations of the protonated molecular species ([M + H]+) and of selected fragment ions allowed proposals for the main fragmentation pathways of compounds of this type.
Pedro Domingues, M. Rosário M. Domingues, António J. Ferrer-Correia, Leszek Czuchajowski, Mariusz P. Gajewski   +4 more
openaire   +3 more sources