Results 41 to 50 of about 854 (179)
Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective
Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez +75 morewiley +1 more sourceMulticentric Experience in Distal-to-Proximal Revascularization of Tandem Occlusion Stroke Related to Internal Carotid Artery Dissection.
, 2018 BACKGROUND AND PURPOSE
Internal carotid dissection is a frequent cause of ischemic stroke in young adults. It may cause tandem occlusions in which cervical carotid obstruction is associated with intracranial proximal vessel occlusion.Arnold, Marcel, Gralla, J., P. Mordasini, Machi, P., J. Gralla, Eker, O F, M. Bühlmann, Bonafé, A, Gralla, Jan, Fischer, Urs, Arnold, Maurice, Bühlmann, M., Jung, S., Fischer, U., Riquelme, C, A. Bonafé, Mordasini, P., Bonafe, Alain, Mordasini, Pasquale, Jung, Simon, U. Fischer, S. Jung, O.F. Eker, Arnold, M., Marnat, G., P. Machi, Bühlmann, Monika, Costalat, Vincent, M. Arnold, C. Riquelme, Eker, Omer Faruk, G. Marnat, V. Costalat, Riquelme, C., Costalat, V, Machi, P, Marnat, G +36 morecore +1 more sourceAntithrombotic regimen in emergent carotid stenting for acute ischemic stroke due to tandem occlusion: a meta-analysis of aggregate data.
, 2023 BACKGROUND
The periprocedural antithrombotic regimen might affect the risk-benefit profile of emergent carotid artery stenting (eCAS) in patients with acute ischemic stroke (AIS) due to tandem lesions, especially after intravenous thrombolysis.Li, W., Cirillo, L., Nguyen, T.N., Hwang, Yang-Ha, Peschillo, Simone, Bracco, Sandra, Li, Wei, Nguyen, Thanh N., Peschillo, S., Fischer, Urs, Maurer, Christoph Johannes, Aguiar de Sousa, Diana, Diana, F., Bracco, S., Aguiar de Sousa, D., Diana, Francesco, Abdalkader, M., Hwang, Y.H., Pop, Raoul, Maurer, C.J., Kaesmacher, J., Kaesmacher, Johannes, Da Ros, V., Fischer, U., Pop, R., Katsanos, Aristeidis H., Zini, A., Ribo, M., Abdalkader, Mohamad, Da Ros, Valerio, Tomasello, A., Bartolini, Bruno, Ribo, Marc, Bartolini, B., Behme, Daniel, Tomasello, Alejandro, Marnat, G., Katsanos, Aristeidis H, Zini, Andrea, Nguyen, Thanh N, Katsanos, A.H., Marnat, Gaultier, Romoli, Michele, Behme, D., Romoli, M., Cirillo, Luigi +45 morecore +1 more sourceInfusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman +18 morewiley +1 more sourceAdaptive Antithrombotic Strategy for Tandem Occlusion Stroke: Escalating Therapy After Thrombectomy and Stenting
DiagnosticsBackground/Objectives: There is no consensus on standardized treatment algorithms for patients with acute ischemic stroke due to anterior circulation tandem occlusions.Gregory Howaldt, Mara Thut, Miklos Krepuska, Patrick Thurner, Jawid Madjidyar, Anna Kyselyova, Susanne Wegener, Christoph Globas, Andreas Luft, Tilman Schubert, Lars Michels, Zsolt Kulcsar +11 moredoaj +1 more sourceEfficacy and Safety of Endovascular Treatment in Acute Tandem Carotid Occlusions: Analysis of a Single-Center Cohort
Cerebrovascular Diseases Extra, 2020 Introduction: Acute ischemic strokes with tandem occlusions, which represent 10–20% of all ischemic strokes, have a particularly poor prognosis. Since emergent treatment of tandem lesions has not been specifically addressed in randomized trials, there is Santiago Fernández Menéndez, Eduardo Murias Quintana, Pedro Vega Valdés, Edison Morales Deza, Elena López-Cancio, Lorena Benavente Fernández, Montserrat González Delgado, Maria Rico-Santos, Sergio Calleja Puerta, Davinia Larrosa Campo +9 moredoaj +1 more sourceMolecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation
Advanced Science, EarlyView.VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo +15 morewiley +1 more source
