Results 241 to 250 of about 138,571 (312)

Human Milk Oligosaccharides Multivalently Presented on Defined Synthetic Neo-Glycoproteins Are Nanomolar Ligands of Tandem-Repeat Galectins. [PDF]

Biomacromolecules
Červený J, Heine V, Hovorková M, Brož P, Filipová E, Kulik N, Hubálek M, Cvačka J, Petrásková L, Florencio-Zabaleta M, Delgado S, Pelantová H, Bosáková Z, Elling L, Jiménez-Barbero J, Ardá A, Křen V, Bojarová P.   +17 more
europepmc   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

Advanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong, Sergio Montalvo Vargo, Gaku Hatanaka, Zhaoyu Gong, Noah Stanis, Jasmine Zhou, Tiphaine Belloir, Ruikang K. Wang, Wyeth Bair, Maysamreza Chamanzar, Azadeh Yazdan‐Shahmorad   +10 more
wiley   +1 more source

Tandem repeat disorders: from diagnosis to emerging therapeutic strategies. [PDF]

Encephalitis
Moon J.
europepmc   +1 more source

Evolution of tandem repeats in putative circumsporozoite protein to enhance its function: A recent and exclusive event in Plasmodium vivax in India

Manoswini Dash, Veena Pande, Aparup Das, Abhinav Sinha   +3 more
openalex   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Genome-wide profiling of short tandem repeat somatic instability reveals associations with age, sex and brain-related traits

Hu J, Mantey R, Guo H, Sidky AM, Touhidinia M, Butt T, Sobhani R, Estrada S, Haendler K, Zhao S, Shang X, De Domenico E, Beyer MD, Breteler MMB, Aziz NA.   +14 more
europepmc   +1 more source

STRPsearch: fast detection of structured tandem repeat proteins. [PDF]

Bioinformatics
Mozaffari S, Arrías PN, Clementel D, Piovesan D, Ferrari C, Tosatto SCE, Monzon AM.   +6 more
europepmc   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Typing of <i>Yersinia pestis</i> in Challenging Forensic Samples Through Targeted Next-Generation Sequencing of Multilocus Variable Number Tandem Repeat Regions. [PDF]

Microorganisms
Yun H, Lee SH, Gu SH, Lim SH, Song DH.
europepmc   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source