The Anticancer Perspective of Tangeretin: A Small Review [PDF]
MoleculesCancer is an important disease that threatens human life and health. Many natural compounds from plants have been found to have a better inhibitory effect on cancer, and flavonoids are one of them.
Yuan Xu +3 more
doaj +4 more sources
Microencapsulation of Tangeretin in a Citrus Pectin Mixture Matrix [PDF]
Foods, 2020 The objectives of this research were to microencapsulate tangeretin, and to evaluate the basic characteristics of the microcapsule products. Tangeretin is a polymethoxyflavone (PMF) which has been revealed to possess various health benefits and is ...
Xiuxiu Sun +4 more
doaj +3 more sources
Tangeretin protects renal tubular epithelial cells against experimental cisplatin toxicity [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Cisplatin is an effective antineoplastic agent; its clinical utility, however, is limited by a few salient toxic side effects like nephrotoxicity.
Saeed Nazari Soltan Ahmad +9 more
doaj +3 more sources
Tangeretin Unravels Metabolic Dysfunction-Associated Fatty Liver Disease in Rats by Enhancing the IRS/Akt Pathway [PDF]
LifeExcessive high-fat diet (HFD) intake can precipitate metabolic dysfunction-associated fatty liver disease (MAFLD). Tangeretin is a citrus flavonoid possessing many biological properties.
Ittipon Yuenyong +6 more
doaj +2 more sources
Optimization of Nano-Tangeretin Recrystallization via Natural Surfactants in the Antisolvent Precipitation Process: Physicochemical Characterization and Antioxidant Activity [PDF]
NanomaterialsIn this study, an improved method combining natural surfactants with a solvent–antisolvent precipitation technique was developed to prepare highly effective nano-sized tangeretin particles.
Yan Huang +3 more
doaj +2 more sources
Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis. [PDF]
PLoS ONE, 2016 Despite its broad applications, cisplatin affords considerable nephro- and hepatotoxicity through triggering inflammatory and oxidative stress cascades.
Hany A Omar +3 more
doaj +3 more sources
Prospects of tangeretin as a modulator of cancer targets/pathways
Pharmacological Research, 2020 To date, cancer is the second leading cause of death worldwide after cardiac arrest. A large number of synthetic drugs are available for the treatment of different types of cancer; however, a major problem associated with these drugs is its toxicity towards the normal cells.
Suaib Luqman, Abha Meena
exaly +3 more sources
Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway [PDF]
Chinese MedicineBackground Sepsis-induced acute lung injury (ALI) is a severe clinical condition accompanied with high mortality. Tangeretin, which is widely found in citrus fruits, has been reported to exert antioxidant and anti-inflammatory properties.
Hui Zhang +8 more
doaj +2 more sources
Identification of key targets and exploration of therapeutic molecular mechanisms of natural compound tangeretin in osteosarcoma [PDF]
Discover OncologyIntroduction Osteosarcoma (OS) is an invasive and lethal malignancy showing a low 5 year survival rate, underscoring the need for identifying new therapeutic targets and their inhibitors to enhance prevention and treatment strategies.
Ruoping Yanzhang +7 more
doaj +2 more sources
Anticancer Potential of Flavonoids: An Overview with an Emphasis on Tangeretin
Pharmaceuticals, 2023 Natural compounds with pharmacological activity, flavonoids have been the subject of an exponential increase in studies in the field of scientific research focused on therapeutic purposes due to their bioactive properties, such as antioxidant, anti ...
Francisco Canindé Ferreira de Luna +3 more
doaj +3 more sources